Now showing items 1-20 of 24

    • Montero, David; Vidal, Maricel; Pardo, Mirka; Torres, Alexia; Kruger, Eduardo; Farfán Urzúa, Mauricio; O'Ryan Gallardo, Miguel; Fleckenstein, James; Canto Fuentes, Felipe del; Vidal Álvarez, Roberto; Luo, Qingwei (Elsevier, 2017)
      In March 2010, a massive outbreak of gastroenteritis started in the region of Antofagasta (northern Chile). The outbreak was mainly attributed to Norovirus genogroup II although ETEC strains were also isolated with high ...
    • Vidal Álvarez, Roberto; Muhsen, Khitam; Tennant, Sharon M.; Svennerholm, Ann Mari; Sow, Samba O.; Sur, Dipika; Zaidi, Anita K.M.; Faruque, Abu S.G.; Saha, Debasish; Adegbola, Richard; Hossain, M. Jahangir; Alonso, Pedro L.; Breiman, Robert F.; Bassat, Quique; Tamboura, Boub (Public Library of Science, 2019)
      Background: Enterotoxigenic Escherichia coli (ETEC) encoding heat-stable enterotoxin (ST) alone or with heat-labile enterotoxin (LT) cause moderate-to-severe diarrhea (MSD) in developing country children. The Global Enteric ...
    • Vidal Álvarez, Roberto; Caballero, B.; Couve Correa, Andrés; Hetz Flores, Claudio (Bentham Science Publishers Ltd., 2011)
      A variety of neurological diseases including Huntington’s disease (HD), Alzheimer’s disease and Parkinson’s disease share common neuropathology, primarily featuring the presence of abnormal protein inclusions containing ...
    • Montero, David Arturo; Canto, Felipe del; Velasco, Juliana; Colello, Rocío; Padola, Nora Lia; Salazar, Juan Carlos; Martín, Carla San; Oñate, Ángel; Blanco, Jorge; Rasko, David A.; Contreras, Carmen; Puente, José Luis; Scheutz, Flemming; Franz, Eelco; Vidal Álvarez, Roberto (Taylor and Francis, 2019)
      Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens causing severe gastroenteritis, which may lead to hemolytic uremic syndrome. The Locus of Enterocyte Effacement (LEE), a Pathogenicity Island (PAI), is ...
    • Sobarzo Aguayo, Gustavo; Martínez Tagle, María Angélica; Vidal Álvarez, Roberto; Martínez Torrens, María Cristina; Avendaño Carvajal, Luis (FEDERACION BIOQUIMICA PROVINCIA BUENOS AIRES, 2006-12)
      Up to 80% of cell cultures have been reported to be contaminated with Mollicutes, causing unreliable experimental results and giving rise to unsafe biological products. The aims of this study were to estimate the frequency ...
    • Reyes S., Marcelo; Torres Torretti, Juan Pablo; Prado Jiménez, Valeria; Vidal Álvarez, Roberto (SOC MEDICA SANTIAGO, 2008-03)
      Acute bacterial meningitis (ABM) is a serious disease that needs rapid diagnosis for an accurate treatment. The most important etiological agents are: Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus ...
    • Gallardo Schall, Pablo; Izquierdo, Mariana; Vidal Álvarez, Roberto; Chamorro Veloso, Nayaret; Rossello Mora, Ramón; O'Ryan Gallardo, Miguel; Farfán Urzúa, Mauricio (Frontiers media SA, 2017)
      Background: Diarrheagenic Escherichia coli (DEC) strains are a major cause of diarrhea in children under 5 years of age worldwide. DEC pathogenicity relies on the interaction of bacteria with environmental factors, including ...
    • Vidal, Maricel; Escobar Oliva, Paula; Prado Jiménez, Valeria; Hormazábal, Juan Carlos; Vidal Álvarez, Roberto (2007)
      The distribution of three putative adhesin genes in 123 Shiga toxin-producing (STEC) strains was determined by PCR. The STEC strains were isolated from human patients (n = 90) and food (n = 33) and were characterized by ...
    • Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriela; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (Elsevier, 2014)
      Crohn’s disease (CD) is a multifactorial pathology associated with the presence of adherent-invasiveEscherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in otherintestinal pathologies ...
    • Torres, Alfredo G.; Blanco, Miguel; Valenzuela, Patricio; Slater, Terry M.; Patel, Shilpa D.; Dahbi, Ghizlane; López, Cecilia; Barriga, Ximena Fernández; Blanco, Jesús E.; Gomes, Tânia A.T.; Vidal Álvarez, Roberto; Blanco, Jorge (2009)
      Lpf (stands for long polar fimbriae) is one of the few adhesive factors of enterohemorrhagic Escherichia coli O157:H7 associated with colonization of the intestine. E. coli O157:H7 strains possess two lpf loci encoding ...
    • Gallardo Schall, Pablo; Izquierdo Tramon, Mariana; Vidal Álvarez, Roberto; Soto Barrientos, Francisco; Ossa Alemparte, Juan; Farfán Urzúa, Mauricio (Frontiers Media, 2020)
      Background:DiarrheagenicEscherichia coli(DEC) strains are a main cause of diarrhea worldwide in children under 5 years old. DEC virulence is strongly regulated by environmental conditions and metabolites produced by the ...
    • Montero Forero, David; Canto Fuentes, Felipe del; Salazar Garrido, Juan Carlos; Céspedes Ulloa, Sandra; Cádiz Núñez, Leandro; Arenas Salinas, Mauricio; Reyes, José; Oñate, Ángel; Vidal Álvarez, Roberto (Nature, 2020)
      Shiga toxin-producing Escherichia coli (STEC) cause diarrhea and dysentery, which may progress to hemolytic uremic syndrome (HUS). Vaccination has been proposed as a preventive approach against STEC infection; however, ...
    • Montero, David; Velasco Martínez, Lucia Juliana; Canto Fuentes, Felipe del; Puente, José L.; Padola, Nora L.; Rasko, David A.; Farfán Urzúa, Mauricio; Salazar Garrido, Juan; Vidal Álvarez, Roberto (Nature Publishing Group, 2017)
      Shiga Toxin-producing Escherichia coli (STEC) are a group of foodborne pathogens associated with diarrhea, dysentery, hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). Shiga toxins are the major virulence factor ...
    • Kohansal, M.; Najafi, A.; Vidal Álvarez, Roberto (Hellenic Veterinary Medical, 2020)
      Intensive antibiotics' use in the management of the disease in neonate calves, a major economic concern in bovine industry, is one of the contributors to high levels of antibiotic resistance of pathogenic bacteria. The ...
    • Batista González, Ana; Vidal Álvarez, Roberto; Criollo Céspedes, Alfredo; Carreño Márquez, Leandro (Frontiers Media, 2020)
      Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
    • Vidal Álvarez, Roberto; Roessler, Patricia; Solari, Verónica; Vollaire, Jimena; Jiang, Xi; Matson, David O.; Mamani, Nora; Prado Jiménez, Valeria; O'Ryan Gallardo, Miguel (AMER SOC MICROBIOLOGY, 2006-06)
      Capsid and polymerase (RdRp) genes of 13 norovirus outbreak strains from Chile were compared. The genes sequences were discordant for five strains, and recombination was confirmed for two of them by amplification of a ...
    • O'Ryan Gallardo, Miguel; Peña, Alfredo; Vergara, Rodrigo; Díaz, Janepsy; Mamani Manzano, Nora; Cortés, Héctor; Lucero Álvarez, Yalda; Vidal Álvarez, Roberto; Osorio Abarzúa, Carlos Gonzalo; Santolaya de Pablo, María Elena; Hermosilla Díaz, Germán; Prado Jiménez, Valeria (Lippincott Williams, 2010)
      Rotavirus and more recently noroviruses are recognized as main causes of moderate to severe acute diarrhea episodes (ADE) in children < or =5 years of age. Comparing epidemiologic and clinical features of norovirus to ...
    • Bustamante, Paula; Vidal Álvarez, Roberto (Frontiers Media, 2020)
      Adherent-invasive Escherichia coli (AIEC) corresponds to an E. coli pathovar proposed as a possible agent trigger associated to Crohn's disease. It is characterized for its capacity to adhere and to invade epithelial cells, ...
    • Ortiz Román, Luisa; Riquelme Neira, Roberto; Vidal Álvarez, Roberto; Oñate, Ángel (Elsevier, 2014)
      One of the properties of bacteria is their capacity to acquire large fragments of genomic DNA from other bacteria or to loose important parts of their own genome. Such fragments include genomic islands (GIs); nine GIs ...
    • Vidal, Maricel; Kruger, Eileen; Durán, Claudia; Lagos, Rosanna; Levine, Myron; Prado Jiménez, Valeria; Toro, Cecilia; Vidal Álvarez, Roberto (AMER SOC MICROBIOLOGY, 2005-10)
      We designed a multiplex PCR for the detection of all categories of diarrheagenic Escherichia coli. This method proved to be specific and rapid in detecting virulence genes from Shiga toxin-producing (stx(1), stx(2), and ...