Browsing by Author "0675a0b3-963a-45ef-bb17-eb7d56844da8"

Now showing items 1-3 of 3

    • Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response 
      Díaz, María I.; Díaz, Paula; Castillo Bennett, Jimena; Urra, Hery; Ortiz, Rina; Contreras Orellana, Pamela; Hetz Flores, Claudio; Quest, Andrew F. G. (Springer Nature, 2020)
      Caveolin-1 (CAV1), is a broadly expressed, membrane-associated scaffolding protein that acts both, as a tumor suppressor and a promoter of metastasis, depending on the type of cancer and stage. CAV1 is downregulated in ...
    • Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma ... 
      Guerrero, Simón; Díaz García, Víctor; Contreras-Orellana, Pamela; Muñoz Lara, Pablo; Palma, Sujey; Guzmán, Fanny; Lobos González, Lorena; Cárdenas, Areli; Rojas Silva, Ximena; Muñoz, Luis; Leyton Campos, Lisette; Kogan Bocian, Marcelo; Quest, Andrew F. G. (Future Medicine, 2018-06)
      Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10(CAV1)) or lacking CAV1 (B16F10(mock)) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing ...
    • Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells 
      Ortiz, Rina; Díaz, Jorge; Díaz Valdivia, Natalia; Martínez Meza, Samuel; Simón, Layla; Contreras Orellana, Pamela; Lobos González, Lorena; Guerrero, Simón; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2020)
      In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...