Now showing items 1-3 of 3

    • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones 

      Aguirre, G.; Boiani, Lucía; Cerecetto, Hugo; Fernández, M.; González, M.; Denicola, Ana; Otero, L.; Gambino, Dinorah; Rigol Olsen, Carolina; Olea Azar, Claudio; Faúndez Cáceres, Mario Antonio (PERGAMON-ELSEVIER SCIENCE LTD, 2004-09-15)
      The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis, are described. The designed compounds combine ...
    • Nitrofurylsemicarbazone rhenium and ruthenium complexes as anti-trypanosomal agents 

      Otero, Lucía; Aguirre, Gabriela; Boiani, Lucía; Denicola, Ana; Rigol Olsen, Carolina; Olea Azar, Claudio; Maya Arango, Juan; Morello Casté, Antonio; González, Mercedes; Gambino, Dinorah; Cerecetto, Hugo (ELSEVIER, 2006-11)
      Rhenium and ruthenium complexes of the type [(ReOCl2)-O-V(PPh3)L] and [(RuC2)-C-II(DMSO)(2)L], where L are 5-nitroftitylsemicarbazone derivatives, were prepared in an effort to obtain new anti-trypanosomal agents combining ...
    • Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets 

      Otero, Lucía; Vieites, Marisol; Boiani, Lucía; Denicola, Ana; Rigol Olsen, Carolina; Opazo, Lucía; Olea Azar, Claudio; Maya Arango, Juan; Morello Casté, Antonio; Krauth Siegel, R. Luise; Piro, Oscar E.; Castellano, Eduardo; González, Mercedes; Gambino, Dinorah; Cerecetto, Hugo (AMER CHEMICAL SOC, 2006-06-01)
      In the search for new therapeutic tools against American Trypanosomiasis palladium complexes with bioactive nitrofuran-containing thiosemicarbazones as ligands were obtained. Sixteen novel palladium (II) complexes with the ...