Browsing by Author "110300f1-de06-4784-8720-c65e5c20a491"

Now showing items 1-2 of 2

    • A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration ... 
      Catalan-Figueroa, Johanna; Boisset, Constanza B.; Jara, Miguel O.; Flores, Mario E.; Moreno-Villoslada, Ignacio; Fiedler, Jenny L.; Morales, Javier O. (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Oral bioavailability of loperamide is restricted by its limited absorption in the gastrointestinal tract due to its poor aqueous solubility and its P-glycoprotein (Pgp) substrate characteristic. In ...
    • Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically ... 
      Román Albasini, Luciano; Díaz Véliz, Gabriela; Olave, Felipe Antonio; Aguayo, Felipe Ignacio; García Rojo, Gonzalo; Corrales, Wladimir Antonio; Silva, Juan Pablo; Ávalos, Ana María; Rojas, Paulina S.; Aliaga, Esteban; Fiedler, Jenny Lucy (Elsevier, 2020)
      Several lines of evidence suggest that antidepressant drugs may act by modulating neuroplasticity pathways in key brain areas like the hippocampus. We have reported that chronic treatment with fasudil, a Rho-associated protein ...