Now showing items 1-7 of 7

    • Schenck, Thilo L.; Chávez, Myra N.; Condurache, Alexandru P.; Hopfner, Úrsula; Rezaeian, Farid; Machens, Hans Günther; Egaña, José T. (JOURNAL OF VISUALIZED EXPERIMENTS, 2014)
      Insufficient vascularization is considered to be one of the main factors limiting the clinical success of tissue-engineered constructs. In order to evaluate new strategies that aim at improving vascularization, reliable ...
    • Alvarez, Marjorie; Reynaert, Nicole; Chávez, Myra N.; Aedo, Geraldine; Araya, Francisco; Hopfner, Úrsula; Fernández Hidalgo, Juan; Allende Connelly, Miguel; Egaña, José T. (Public Library Science, 2015)
      The extreme dependence on external oxygen supply observed in animals causes major clinical problems and several diseases are related to low oxygen tension in tissues. The vast majority of the animals do not produce oxygen ...
    • Wahl, Elizabeth A.; Fierro, Fernando A.; Peavy, Thomas R.; Hopfner, Úrsula; Dye, Julian F.; Machens, Hans Günther; Egaña, José T.; Schenck, Thilo L. (Hindawi, 2015)
      Mesenchymal stemcells (MSCs) have been shown to improve tissue regeneration in several preclinical and clinical trials. These cells have been used in combination with three-dimensional scaffolds as a promising approach in ...
    • Schenck, Thilo Ludwig; Hopfner, Úrsula; Chávez, Myra Noemi; Machens, Hans Günther; Somlai Schweiger, Ian Andreas; Giunta, Riccardo Enzo; Viola Bohne, Alexandra; Nickelsen, Jörg; Allende Connelly, Miguel; Egaña, José Tomás (Elsevier, 2015)
      Engineered tissues are highly limited by poor vascularization in vivo, leading to hypoxia. In order to overcome this challenge, we propose the use of photosynthetic biomaterials to provide oxygen. Since photosynthesis is ...
    • Zhang, Ziyang; Ito, Wulf D.; Hopfner, Úrsula; Böhmert, Björn; Kremer, Mathias; Reckhenrich, Ann K.; Harder, Yves; Lund, Natalie; Kruse, Charli; Machens, Hans Günther; Egaña, José T. (Elsevier, 2011)
      Increasing evidence suggests that vascular resident endothelial progenitor cells (VR-EPCs) are present in several organs, playing an important role in postnatal neovascularization. Here, we isolated and characterized VR-EPCs ...
    • Rosas, M. N. C.; Schenck, Thilo L.; Hopfner, Úrsula; Centeno, C.; Machens, Hans Günther; Somlai Schweiger, Ian Andreas; Heikenwaelder, M.; Bono Merino, María Rosa; Schwarz, C.; Nickelsen, Jörg; Allende Connelly, Miguel; Egaña, J. T. (Mary Ann Liebert, 2015)
    • Egaña, José T.; Fierro, Fernando Antonio; Krueger, Stefan; Bornhaeuser, Martin; Huss, Ralf; Lavandero González, Sergio; Machens, Hans-Guenther (Mary Ann Liebert, 2009)
      All engineered bioartificial structures developed for tissue regeneration require oxygen and nutrients to establish proper physiological functions. Aiming to improve vascularization during dermal regeneration, we combined ...