Browsing by Author "1db0bfc1-4f17-4b03-8f7a-f1f7b243ec5c"

Now showing items 1-4 of 4

    • Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies ... 
      Zúñiga, Roberto A.; Gutiérrez-González, Matías; Collazo, Norberto; Sotelo, Pablo Hérnan; Ribeiro, Carolina H.; Altamirano, Claudia; Lorenzo, Carmen; Aguillón, Juan Carlos; Molina, María Carmen (BioMed Central Ltd., 2019)
      Background: The production of recombinant proteins in mammalian cell lines is one of the most important areas in biopharmaceutical industry. Viral transcriptional promoters are widely used to express recombinant proteins ...
    • Engineering a defined culture medium to grow Piscirickettsia salmonis for its use in vaccine formulations 
      Fuentealba, Pablo; Latorre, Yesenia; González, Ernesto; Martínez Basterrechea, Irene; Soto, Carmen; Altamirano, Claudia (Springer, 2020)
      Piscirickettsia salmonis is a facultative Gram-negative intracellular bacterium that produces piscirickettsiosis, disease that causes a high negative impact in salmonid cultures. The so-far-unidentified nutritional ...
    • The Pros and Cons of Using Algal Polysaccharides as Prebiotics 
      Gotteland, Martin; Riveros Cárcamo, Karla; Gasaly, Naschla; Cárcamo, Constanza; Magne, Fabien; Liabeuf Altamirano, Gianella; Beattie, Alejandra; Rosenfeld Sekulovic, Sebastián (Frontiers Media, 2020)
      Macroalgae stand out for their high content of dietary fiber (30-75%) that include soluble, sulfated (fucoidan, agaran, carrageenan, and ulvan) and non-sulfated (laminaran and alginate) polysaccharides. Many studies indicate ...
    • Transcription factor engineering in CHO cells for recombinant protein production 
      Gutiérrez-González, Matías; Latorre, Yesenia; Zúñiga, Roberto; Aguillón, Juan Carlos; Molina, María Carmen; Altamirano, Claudia (Taylor and Francis Ltd, 2019)
      The continuous increase of approved biopharmaceutical products drives the development of more efficient recombinant protein expression systems. Chinese hamster ovary (CHO) cells are the mainstay for this purpose but have ...