Now showing items 1-20 of 70

    • A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus 

      DebRoy, Sruti; Saldaña, Miguel; Travisany, Dante; Montano, Andrew; Galloway Peña, Jessica; Horstmann, Nicola; Yao, Hui; González Canales, Mauricio; Maass Sepúlveda, Alejandro; Latorre Mora, Mauricio; Shelburne, Samuel (Nature Publishing Group, 2016)
      Catabolite control protein A (CcpA) is a highly conserved, master regulator of carbon source utilization in gram-positive bacteria, but the CcpA regulon remains ill-defined. In this study we aimed to clarify the CcpA regulon ...
    • Asymptotic randomization of subgroup shifts by linear cellular automata 

      Maass Sepúlveda, Alejandro; Martínez Aguilera, Servet; Marcus, Pivato; Yassawi, Reem (CAMBRIDGE UNIV PRESS, 2006-08)
      Let M = N-D be the positive orthant of a D-dimensional lattice and let (G, +) be a finite abelian group. Let G subset of G(M) be a subgroup shift, and let mu be a Markov random field whose support is G. Let Phi : G -> G ...
    • Bioinformatic survey for new physiological substrates of Cyclin-dependent kinase 5 

      Bórquez Muñoz, Daniel; Olmos, Cristina; Álvarez, Sebastián; Genova, Alex Di; Maass Sepúlveda, Alejandro; González Billault, Christian (Elsevier, 2013)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase predominantly active in the nervous system where it regulates several processes such as neuronal migration, cytoskeletal dynamics, axonal ...
    • Calcium/calmodulin-dependent protein kinase type IV Is a target gene of the Wnt/β-catenin signaling pathway 

      Arrázola, Macarena S.; Varela Nallar, Lorena; Colombres, Marcela; Toledo, Enrique M.; Cruzat, Fernando; Pavez, Leonardo; Assar, Rodrigo; Aravena, Andrés; González, Mauricio; Montecino, Martín; Maass Sepúlveda, Alejandro; Martínez Aguilera, Servet; Inestrosa, Nibaldo C. (2009)
      Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory ...
    • Cálculo de nilfactores maximales en extensiones por cociclo de una rotación minimal 

      Pardo Jaqueih, Ángel Alonso (Universidad de Chile, 2012)
      La presente memoria tiene por objetivo principal el estudio de nilsistemas que aparecen como factores -los nilfactores- de sistemas dinámicos que se obtienen como extensiones por cociclo de una rotación minimal. El estudio ...
    • Cdk5 regulates Rap1 activity 

      Utreras Puratich, Elías; Henríquez, Daniel R.; Contreras Vallejos, Erick; Olmos, Cristina; Di Genova, Alex; Maass Sepúlveda, Alejandro; Kulkarni, Ashok B.; González Billault, Christian (2013)
      Rap1 signaling is important for migration, differentiation, axonal growth, and during neuronal polarity. Rap1 can be activated by external stimuli, which in turn regulates specific guanine nucleotide exchange factors such ...
    • Characterization of minimal sequences associated with self similar interval exchange maps 

      Cobo, Milton; Gutiérrez Romo, Rodolfo Joaquín; Maass Sepúlveda, Alejandro (IOP Publishing Ltd, 2018)
      The construction of affine interval exchange maps (IEMs) with wandering intervals that are semi-conjugate to a given self-similar IEM is strongly related to the existence of the so-called minimal sequences associated with ...
    • Coding with variable block maps 

      Acuña, Vicente; Didier, Gilles; Maass Sepúlveda, Alejandro (ELSEVIER, 2006-12-15)
      In this article we study a special class of sliding block maps that we call variable block maps.We characterize the subsets of ï¬ nite and inï¬ nite sequences that can be obtained as the image of another subset of symbolic ...
    • Comparación Teórica de las Capacidades Metabólicas de Saccharomyces Cerevisiae y Pichia Pastoris para la Producción de SOD 

      Cominetti Allende, Ornella Cecilia (Universidad de ChilePrograma Cybertesis, 2007)
    • Comparative gene expression analysis of Dtg, a novel target gene of Dpp signaling pathway in the early Drosophila melanogaster embryo 

      Hödar Quiroga, Christian; Zúñiga, Alejandro; Pulgar Tejo, Rodrigo; Travisany, Dante; Chacón, Carlos; Pino, Michael; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Liliana (Elsevier, 2014)
      In the early Drosophila melanogaster embryo, Dpp, a secreted molecule that belongs to the TGF-β superfamily of growth factors, activates a set of downstream genes to subdivide the dorsal region into amnioserosa and ...
    • Comparative genomic analysis of carbon and nitrogen assimilation mechanisms in three indigenous bioleaching bacteria: predictions and validations 

      Levicán, Gloria; Ugalde, Juan A.; Ehrenfeld, Nicole; Maass Sepúlveda, Alejandro; Parada, Pilar (BIOMED CENTRAL LTD, CURRENT SCIENCE GROUP, 2008-12-03)
      Background: Carbon and nitrogen fixation are essential pathways for autotrophic bacteria living in extreme environments. These bacteria can use carbon dioxide directly from the air as their sole carbon source and can use ...
    • Complejidad Comunicacional y Universalidad Intrínseca en Autómatas Celulares Unidimensionales 

      Briceño Domínguez, Raimundo José (Universidad de ChileCyberDocs, 2011)
      Encontrar buenas cotas inferiores y condiciones necesarias para nociones de complejidad y universalidad es uno de los mayores desafíos en el área de la informática teórica. En este sentido, la teoría de la complejidad ...
    • Complejidad Topológica de Nilsistemas y Aplicaciones 

      Donoso Fuentes, Sebastián Andrés (Universidad de Chile, 2011)
      El presente trabajo de memoria tiene por objetivo principal el estudio de propiedades topológicas de la clase de sistemas dinámicos llamados nilsistemas. Esta clase de sistemas dinámicos ha ganado importancia desde la ...
    • Complete genome sequence of Piscirickettsia salmonis LF-89 (ATCC VR-1361) a major pathogen of farmed salmonid fish 

      Pulgar Tejo, Rodrigo; Travisany, Dante; Zúñiga, Alejandro; Maass Sepúlveda, Alejandro; Cambiaso Ayala, Liliana (Elsevier, 2015)
      Piscirickettsia salmonis, the causative agent of salmonid rickettsial septicemia (SRS), is a significant threat to the healthy and sustainable production of salmonid farming industry. This Gram-negative bacterium, originally ...
    • Construction of Reference Chromosome-Scale Pseudomolecules for Potato: Integrating the Potato Genome with Genetic and Physical Maps 

      Sharma, Sanjeev Kumar; Bolser, Daniel; de Boer, Jan; Sønderkær, Mads; Amoros, Walter; Carboni, Martín Federico; D'Ambrosio, Juan Martín; Cruz, Germán de la; Di Genova, Alex; Douches, David S.; Eguiluz, María; Guo, Xiao; Guzman, Frank; Hackett, Christine A.; Hamilton, John P.; Guangcun, Li; Li, Ying; Lozano, Roberto; Maass Sepúlveda, Alejandro; Marshall, David; Martinez, Diana; McLean, Karen; Mejía, Nilo; Milne, Linda; Munive, Susan; Nagy, Istvan; Ponce, Olga; Ramirez, Manuel; Simon, Reinhard; Thomson, Susan J.; Torres, Yerisf; Waugh, Robbie; Zhang, Zhongua; Huang, Sanwen; Visser, Richard G. F.; Bachem, Christian W. B.; Sagredo, Boris; Feingold, Sergio E.; Orjeda, Gisella; Veilleux, Richard E.; Bonierbale, Merideth; Jacobs, Jeanne M. E.; Milbourne, Dan; Martin, David Michael; Bryan, Glenn J. (2013)
      The genome of potato, a major global food crop, was recently sequenced. The work presented here details the integration of the potato reference genome (DM) with a new sequence-tagged site marker2based linkage map and ...
    • Contribución al Estudio de Embaldosados Aperíodicos: Teoría de Translación y Propiedades Estadísticas 

      Aliste Prieto, José (Universidad de ChilePrograma Cybertesis, 2009)
    • Contribución al estudio de valores propios en sistemas de Bratteli-Vershik de rango finito 

      Frank Marambio, Alexander Leberecht (Universidad de Chile, 2014)
      El objetivo de esta tesis es presentar condiciones para analizar la existencia de valores propios en algunas familias de sistemas de Bratteli-Vershik minimales. Ésto expande los resultados obtenidos hasta el día de hoy en ...
    • Contributions to ergodic theory and topological dynamics: cube structures and automorphisms 

      Donoso Fuentes, Sebastián Andrés (Universidad de Chile, 2015)
      Esta tesis está consagrada al estudio de diferentes problemas en teoría ergódica y dinámica topológica, relacionados a "estructuras de cubos". Consta de seis capítulos. En la presentación general entregamos resultados ...
    • Deciphering transcriptional regulations coordinating the response to environmental changes 

      Acuña Aguayo, Vicente; Aravena, Andrés; Guziolowski, Carito; Eveillard, Damien; Siegel, Anne; Maass Sepúlveda, Alejandro (BioMed Central, 2016)
      Background: Gene co-expression evidenced as a response to environmental changes has shown that transcriptional activity is coordinated, which pinpoints the role of transcriptional regulatory networks (TRNs). Nevertheless, ...
    • Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and overall survival 

      Alvarez, Carolina; Aravena, Andrés; Tapia, Teresa; Rozenblum, Ester; Solís, Luisa; Corvalán, Alejandro; Camus, Mauricio; Acevedo Alvarez, Manuel; Munroe, David; Maass Sepúlveda, Alejandro; Carvallo, Pilar (BioMed Central Ltd., 2016)
      © 2016 Alvarez et al.Background: Array CGH analysis of breast tumors has contributed to the identification of different genomic profiles in these tumors. Loss of DNA repair by BRCA1 functional deficiency in breast cancer ...