Now showing items 1-3 of 3

    • Activating GNAS1 gene mutations in patients with premature thelarche 

      Román, Rossana; Johnson, María Cecilia; Codner Dujovne, Ethel; Boric Scarpa, María Angélica; Ávila, Alejandra; Cassorla Goluboff, Fernando (2004)
      Objective To identify GNAS1 gene mutations in girls with exaggerated and/or chronic fluctuating thelarche for at least 1-year duration with no other signs of precocious puberty, skeletal dysplasia, or typical skin lesions ...
    • Androgen receptor CAG and GGN polymorphisms in boys with isolated hypospadias 

      Parada Bustamante, Alexis; Lardone, María Cecilia; Madariaga, Marcia; Johnson, María Cecilia; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Castro, Andrea (2012)
      Background: The etiology of hypospadias is multifactorial. Abnormal androgenic secretion and/or action during the development of external genitalia may be involved in the etiology of this congenital malformation. This study ...
    • Role of nitric oxide and bcl-2 family genes in the regulation of human endometrial apoptosis 

      Castro, Andrea; Johnson, María Cecilia; Anido, Mabel; Cortinez, Armando; Gabler, Fernando; Vega, Margarita (2002)
      Objective: To investigate the role of nitric oxide (NO) and death regulatory genes, bcl-2 and bax, in human endometria apoptosis.Design: Expression of bcl-2, bax, NO synthases (NOS), and the apoptotic effect of L-arginine ...