Browsing by Author "2e6a59d0-c4c0-43c8-a76d-c5fbc6cb6c76"

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    • Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field ... 
      Young, Rodrigo M.; Hawkins, Thomas A.; Cavodeassi, Florencia; Stickney, Heather L.; Schwarz, Quenten; Lawrence, Lisa M.; Wierzbicki, Claudia; Cheng, Bowie; Luo, Jingyuan; Ambrosio, Elizabeth Mayela; Klosner, Allison; Sealy, Ian M.; Rowell, Jasmine; Trivedi, Chintan A.; Bianco, Isaac H.; Allende Connelly, Miguel; Busch-Nentwich, Elisabeth M.; Gestri, Gaia; Wilson, Stephen W. (Elife Sciences Publ., 2019)
      The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to ...
    • Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis ... 
      Valdivia, Leonardo E.; Young, Rodrigo M.; Hawkins, Thomas A.; Stickney, Heather L.; Cavodeassi, Florencia; Schwarz, Quenten; Pullin, Lisa M.; Villegas, Rosario; Moro, Enrico; Argenton, Francesco; Allende Connelly, Miguel; Wilson, Stephen W. (2011)
      During tissue morphogenesis and differentiation, cells must self-renew while contemporaneously generating daughters that contribute to the growing tissue. How tissues achieve this precise balance between proliferation and ...