Browsing by Author "2ec24c23-b878-49d8-94b4-7ee63c878488"

Now showing items 1-3 of 3

    • NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, ... 
      Bustos, Fernando J.; Jury, Nur; Martínez, Pablo; Ampuero, Estibaliz; Campos, Matías; Abarzua, Sebastián; Jaramillo, Karen; Ibing, Susanne; Mardones, Muriel D.; Haensgen, Henny; Kzhyshkowska, Julia; Tevy, María Florencia; Neve, Rachael; Sanhueza Toha, María Magdalena; Varela Nallar, Lorena; Montecino, Martín; Van Zundert, Brigitte (Wiley, 2017)
      Dendrite arbor growth, or dendritogenesis, is choreographed by a diverse set of cues, including the NMDA receptor (NMDAR) subunits NR2A and NR2B. While NR1NR2B receptors are predominantly expressed in immature neurons and ...
    • Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain ... 
      Calderón Garcidueñas, Lilian; Herrera Soto, Andrea; Jury, Nur; Maher, Bárbara; González Maciel, Angélica; Reynoso Robles, Rafael; Ruiz Rudolph, Pablo; van Zundert, Brigitte; Varela Nallar, Lorena (Elsevier, 2020)
      Exposure to air pollutants is associated with an increased risk of developing Alzheimer's disease (AD). AD pathological hallmarks and cognitive deficits are documented in children and young adults in polluted cities (e.g. ...
    • Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent ... 
      Jury, Nur; Abarzúa, Sebastián; Díaz, Iván; Guerra, Miguel V.; Ampuero, Estibaliz; Cubillos, Paula; Martínez, Pablo; Herrera Soto, Andrea; Arredondo, Cristian; Rojas, Fabiola; Manterola Zúñiga, Marcia; Rojas, Adriana; Montecino, Martín; Varela Nallar, Lorena; van Zundert, Brigitte (BMC, 2020)
      Background Hexanucleotide repeat expansions of the G(4)C(2) motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Tissues ...