Now showing items 1-20 of 44

    • A practical approach to evidence-based dentistry: III: How to appraise and use an article about therapy 

      Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Copyright © 2015 American Dental Association.Background and Overview: Dental practitioners spend most of their time administering treatments. To ensure that their clinical decisions are informed by the best available ...
    • A practical approach to evidence-based dentistry: V: How to appraise and use an article about diagnosis 

      Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Background and Overview Questions regarding diagnosis are common in dental practice. Studies in which investigators apply a diagnostic test and a reference standard to all patients and compare their results represent the ...
    • A practical approach to evidence-based dentistry: VI: How to use a systematic review 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Copyright © 2015 American Dental Association. All rights reserved.Background and Overview. Dental practitioners face new clinical challenges on a daily basis. New treatment options and diagnostic tools are disseminated ...
    • A practical approach to evidence-based dentistry: VII: How to use patient management recommendations from clinical practice guidelines 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon; Neumann, Ignacio; Azarpazhooh, Amir (American Dental Association, 2015)
      © 2015 American Dental Association. All rights reserved.Background and Overview. Clinical practice guidelines represent highly processed evidence with associated recommendations to inform clinical practice and optimize ...
    • A practical approach to evidence-based dentistry: X How to avoid being misled by clinical studies' results in dentistry 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Azarpazhooh, Amir; Glick, Michael; Guyatt, Gordon H. (American Dental Association, 2015)
      © 2015 American Dental Association. Background and Overview Clinicians using evidence to inform decisions on a daily basis have access to a number of tools to help them judge the importance of discriminating studies conducted ...
    • Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis 

      Brignardello Petersen, Romina; Bonner, Ashley; Alexander, Paul E.; Siemieniuk, Reed A. C.; Furukawa, Toshi A.; Rochwerg, Bram; Hazlewood, Glen S.; Alhazzani, Waleed; Mustafa, Reem A.; Murad, M. Hassan; Puhan, Milo A.; Schuenemann, Holger J.; Guyatt, Gordon H. (Elsevier Science INC, 2018)
      This article describes conceptual advances of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group guidance to evaluate the certainty of evidence (confidence in evidence, quality ...
    • Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis 

      Brignardello Petersen, Romina; Bonner, Ashley; Alexander, Paul; Siemieniuk, Reed; Furukawa, Toshi; Rochwerg, Bram; Hazlewood, Glen; Alhazzani, Waleed; Mustafa, Reem; Murad, M. Hassan; Puhan, Milo; Sch€unemann, Holger; Guyatt, Gordon H. (Elsevier, 2018)
      This article describes conceptual advances of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group guidance to evaluate the certainty of evidence (confidence in evidence, quality of ...
    • Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials 

      Kasenda, Benjamín; von Elm, Erik; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari; Neumann, Ignacio; Carrasco Labra, Raúl; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martín A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Public Library Science, 2016)
      Background Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
    • Application of minimal important differences in degenerative knee disease outcomes: a systematic review and case study to inform BMJ Rapid Recommendations 

      Devji, Tahira; Guyatt, Gordon H.; Lytvyn, Lyubov; Brignardello Petersen, Romina; Foroutan, Farid; Sadeghirad, Behnam; Buchbinder, Rachelle; Poolman, Rudolf W.; Harris, Ian A.; Carrasco Labra, Alonso; Siemieniuk, Reed A. C.; Vandvik, Per O. (BMJ Publishing, 2017)
      Objectives: To identify the most credible anchor-based minimal important differences (MIDs) for patient important outcomes in patients with degenerative knee disease, and to inform BMJ Rapid Recommendations for arthroscopic ...
    • Applying GRADE to a network meta-analysis of antidepressants led to more conservative conclusions 

      Bonner, Ashley; Alexander, Paul; Brignardello Petersen, Romina; Furukawa, Toshi; Siemieniuk, Reed A.; Zhang, Yuan; Wiercioch, Wojtek; Florez, Ivan D.; Fei, Yutong; Agarwal, Arnav; Yepes-Nuñez, Juan José; Beyene, Joseph; Schünemann, Holger; Guyatt, Gordon H. (Elsevier USA, 2018)
      © 2018 Objective: To explore the impact of applying the Grading of Recommendations and Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of the evidence in a published network meta-analysis ...
    • Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane review users: study protocol for a randomized controlled trial 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per Olav; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Guyatt, Gordon H.; Schuenemann, Holger (BIOMED CENTRAL, 2015)
      Background: Systematic reviews represent one of the most important tools for knowledge translation but users often struggle with understanding and interpreting their results. GRADE Summary-of-Findings tables have been ...
    • Completion and Publication Rates of Randomized Controlled Trials in Surgery An Empirical Study 

      Rosenthal, Rachel; Kasenda, Benjamin; Dell-Kuster, Salome; Elm, Erik von; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Sohail, Mulla; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Olu, Kelechi K.; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Bradley C., Johnston; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Lippicott Williams & Wilkins, 2015)
      Objective: To investigate the prevalence of discontinuation and nonpublication of surgical versus medical randomized controlled trials (RCTs) and to explore risk factors for discontinuation and nonpublication of surgical ...
    • Corticosteroids for treatment of sore throat: systematic review and meta analysis of randomised trials 

      Sadeghirad, Behnam; Siemieniuk, Reed A. C.; Brignardello Petersen, Romina; Papola, Davide; Lytvyn, Lyubov; Vandvik, Per Olav; Merglen, Arnaud; Guyatt, Gordon H.; Agoritsas, Thomas (BMJ Publishing Group, 2017)
      OBJECTIVE To estimate the benefits and harms of using corticosteroids as an adjunct treatment for sore throat. DESIGN Systematic review and meta-analysis of randomised control trials. DATA SOURCES Medline, ...
    • Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE recommendations 

      Neumann, Ignacio; Alonso Coello, Pablo; Vandvik, Per; Agoritsas, Thomas; Mas, Gemma; Akl, Elie; Brignardello Petersen, Romina; Emparanza, José; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Rojas, Luis; Stirnemann, Jérôme; Irani, Jihad; Hlais, Sani; Mustafa, Reem; Bdair, Fadi; Aly, Abdelrahman; Kristiansen, Annette; Izcovich, Ariel; Ramírez Morera, Anggie; Brozek, Jan; Guyatt, Gordon H.; Schünemann, Holger (Elsevier, 2018-07)
      Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. However, some argue ...
    • Economic analysis studies response 

      Abrahamyan, Lusine; Pechlivanoglou, Petros; Krahn, Murray; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2016)
    • The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses 

      Mustafa, Reem A.; Santesso, Nancy; Brozek, Jan; Akl, Elie A.; Walter, Stephen D.; Norman, Geoff; Kulasegaram, Mahan; Christensen, Robin; Guyatt, Gordon H.; Falck Ytter, Yngve; Chang, Stephanie; Hassan Murad, Mohammad; Vist, Gunn E.; Lasserson, Toby; Gartlehner, Gerald; Shukla, Vijay; Sun, Xin; Whittington, Craig; Post, Piet N.; Lang, Eddy; Thaler, Kylie; Kunnamo, Ilkka; Alenius, Heidi; Meerpohl, Joerg J.; Alba, Ana C.; Nevis, Immaculate F.; Gentles, Stephen; Ethier, Marie Chantal; Carrasco Labra, Raúl; Khatib, Rasha; Nesrallah, Gihad; Kroft, Jamie; Selk, Amanda; Brignardello Petersen, Romina; Schünemann, Holger J. (Elsevier, 2013)
      Objective: We evaluated the inter-rater reliability (IRR) of assessing the quality of evidence (QoE) using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Study Design and Setting: ...
    • GRADE equity guidelines 2: considering health equity in GRADE guideline development: equity extension of the guideline development checklist 

      Akl, Elie A.; Welch, Vivian; Pottie, Kevin; Eslava Schmalbach, Javier; Darzi, Andrea; Sola, Ivan; Katikireddi, Srinivasa Vittal; Singh, Jasvinder; Murad, M. Hassan; Meerpohl, Joerg; Stanev, Roger; Lang, Eddy; Matovinovic, Elizabeth; Shea, Beverley; Agoritsas, Thomas; Alexander, Paul E.; Snellman, Alexandra; Brignardello Petersen, Romina; Gloss, David; Thabane, Lehana; Shi, Chunhu; Stein, Airton T.; Sharaf, Ravi; Brier, Matthias; Guyatt, Gordon H.; Schunemann, Holger; Tugwell, Peter (Elsevier, 2017)
      Objective: To provide guidance for guideline developers on how to consider health equity at key stages of the guideline development process. Study Design and Setting: Literature review followed by group discussions and ...
    • GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction 

      Alonso Coello, Pablo; Schunemann, Holger J.; Moberg, Jenny; Brignardello Petersen, Romina; Akl, Elie A; Davoli, Marina; Treweek, Shaun; Mustafa, Reem A.; Rada, Gabriel; Rosenbaum, Sarah; Morelli, Angela; Guyatt, Gordon H.; Oxman, Andrew D. (BMJ Publishing, 2016)
    • GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines 

      Alonso Coello, Pablo; Oxman, Andrew D.; Moberg, Jenny; Brignardello Petersen, Romina; Akl, Elie A.; Davoli, Marina; Treweek, Shaun; Mustafa, Reem A.; Vandvik, Per O.; Meerpohl, Joerg; Guyatt, Gordon H.; Schunemann, Holger J. (BMJ Publishing, 2016)
    • How to read a systematic review and meta-analysis and apply the results to patient care: Users' guides to the medical literature 

      Murad, Mohammad Hassan; Montori, Victor M.; Ioannidis, John P A; Jaeschke, Roman; Devereaux, P. J.; Prasad, Kameshwar; Neumann, Ignacio; Carrasco Labra, Alonso; Agoritsas, Thomas; Hatala, Rose; Meade, Maureen O.; Wyer, Peter; Cook, Deborah J.; Guyatt, Gordon H. (American Medical Association, 2014)
      Clinical decisions should be based on the totality of the best evidence and not the results of individual studies. When clinicians apply the results of a systematic review or meta-analysis to patient care, they should start ...