Browsing by Author "41311028-6f63-480f-8b4e-99d8a0baa519"

Now showing items 1-3 of 3

    • Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells 
      Li, Q.; Zhu, X.; Ishikura, S.; Zhang, D.; Gao, J.; Sun, Y.; Contreras Ferrat, Ariel Eduardo; Foley, K. P.; Lavandero González, Sergio; Yao, Z.; Bilan, Philip J.; Klip, Amira; Niu, W. (American Physiological Society, 2014)
      Elevating cytosolic Ca2+ stimulates glucose uptake in skeletal muscle, but how Ca2+ affects intracellular traffic of GLUT4 is unknown. In tissue, changes in Ca2++ leading to contraction preclude analysis of the impact of ...
    • Contraction-related stimuli regulate GLUT4 traffic in C2C 12-GLUT4myc skeletal muscle cells 
      Niu, Wenyan; Bilan, Philip J.; Ishikura, Shuhei; Schertzer, Jonathan D.; Contreras Ferrat, Ariel Eduardo; Fu, Zhengxiang; Liu, Jie; Boguslavsky, Shlomit; Foley, Kevin P.; Liu, Zhi; Li, Jinru; Chu, Guilan; Panakkezhum, Thomas; Lopaschuk, Gary D.; Lavandero González, Sergio; Yao, Zhi; Klip (2010)
      Muscle contraction stimulates glucose uptake acutely to increase energy supply, but suitable cellular models that faithfully reproduce this complex phenomenon are lacking. To this end, we have developed a cellular model ...
    • Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles 
      Boguslavsky, Shlomit; Chiu, Tim; Foley, Kevin P.; Osorio-Fuentealba, Cesar; Antonescu, Costin N.; Bayer, K. Ulrich; Bilan, Philip J.; Klip, Amira (2012)
      GLUT4-containing vesicles cycle between the plasma membrane and intracellular compartments. Insulin promotes GLUT4 exocytosis by regulating GLUT4 vesicle arrival at the cell periphery and its subsequent tethering, docking, ...