Browsing by Author "4c7ac9a4-998d-4f6c-b4e0-9a43b7854430"

Now showing items 1-5 of 5

    • Alzheimer's Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats Is Serotype Dependent 
      Díaz Zúñiga, Jaime; More, Jamileth Y.; Melgar Rodríguez, Samanta; Jiménez Unión, Matías; Villalobos Orchard, Francisca; Muñoz Manríquez, Constanza; Monasterio, Gustavo; Valdés Guerrero, José; Vernal, Rolando; Paula-Lima, Andrea (Frontiers Media, 2020)
      Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota that colonizes the gingivodental sulcus. ...
    • Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the ... 
      Cafferatta Chea, Emilio; Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Melgar Rodríguez, Samanta; Rivera Rodríguez, Felipe; Carvajal Pavez, Paola; Hernández Ríos, Emma; Cortés, Bastián; Cortez, Cristian; Cassels Niven, Bruce; Vernal Astudillo, Rolando (Wiley, 2020)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • Increased levels of the T-helper 22-associated cytokine (interleukin-22) and transcription factor (aryl ... 
      Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Rojas, L.; Alvarez, C.; Monasterio, G.; Carvajal Pavez, Paola; Vernal Astudillo, Rolando (Wiley, 2017)
      Background and ObjectiveTwo new T-helper (Th) phenotypes have been recently described and named Th9 and Th22 lymphocytes; however, their role in the pathogenesis of periodontitis remains unclear. This study was aimed to ...
    • Interleukin-35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis 
      Cafferata, Emilio; Terraza Aguirre, Claudia; Barrera, Romina; Faúndez, Nicolás; González, Nicolás; Rojas, Carolina; Melgar Rodríguez, Samanta; Hernández, Marcela; Carvajal, Paola; Cortez, Cristian; González, Fermín; Covarrubias, Cristian; Vernal Astudillo, Rolando (Wiley, 2020)
      Aim T lymphocytes play a central role during the pathogenesis of periodontitis, and the imbalance between the pathogenic T-helper type 17 (Th17) and protective T-regulatory (Treg) lymphocytes determines the tooth-supporting ...
    • The Porphyromonas gingivalis O antigen is required for inhibition of apoptosis in gingival epithelial cells ... 
      Soto, Cristopher; Bugueño Valdebenito, Isaac; Hoare Teuche, Anilei; González, S.; Vengas Díaz, Darna; Melgar Rodríguez, Samanta; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio; Quest, Andrew F. G.; Pérez Donoso, José; Bravo Rodríguez, Denisse (Wiley Blackwell, 2016)
      Background and ObjectivePorphyromonas gingivalis infection induces apoptosis inhibition in gingival epithelial cells; however, it is not fully understood which bacterial effectors are involved in this process. The aim of ...