Now showing items 1-12 of 12

    • Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Neumann, Ignacio; Azarpazhooh, Amir (American Dental Association, 2015)
      © 2015 American Dental Association. All rights reserved.Background and Overview. Clinical practice guidelines represent highly processed evidence with associated recommendations to inform clinical practice and optimize ...
    • Kasenda, Benjamín; von Elm, Erik; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari; Neumann, Ignacio; Carrasco Labra, Raúl; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martín A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Public Library Science, 2016)
      Background Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
    • Agarwal, Arnav; Johnston, Bradley; Vernooij, Robin; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramirez-Morera, Anggie; Selva, Anna; Solà, Ivan; Sanabrai, Andrea; Tikkinen, Kari; Vandvik, Per; Zhang, Yuqing; Zazueta, Oscar; Zhou, Qi; Schunemann, Holger J.; Guyatt, Gordon H.; Alonso Coello, Pablo (Elsevier USA, 2017)
      Objectives Explicit reporting of absolute measures is important to ensure treatment effects are correctly interpreted. We examined the extent to which authors report absolute effects for patient-important outcomes in ...
    • Mendoza, Carolina; Kraemer, Patricia; Herrera, Paloma; Burdiles, Pamela; Sepúlveda, Dino; Nunez, Eliozka; Bernal Muñoz, Cecilia Loreto; Neumann, Ignacio (Sociedad Medica de Santiago, 2017)
      © 2017, Sociedad Medica de Santiago. All rights reserved. The Ministry of Health of Chile, aiming to improve the quality of clinical practice guidelines, gradually incorporated the GRADE system (Grading of Recommendations, ...
    • Mendoza, Carolina; Kraemer, Patricia; Herrera, Paloma; Burdiles, Pamela; Sepúlveda, Dino; Núñez, Eliozka; Muñoz, Cecilia; Neumann, Ignacio (Sociedad Médica Santiago, 2017)
      The Ministry of Health of Chile, aiming to improve the quality of clinical practice guidelines, gradually incorporated the GRADE system (Grading of Recommendations, Assessment, Development and Evaluation) to develop evidence ...
    • Neumann, Ignacio; Alonso Coello, Pablo; Olav Vandvik, Per; Agoritsas, Thomas; Mas, Gemma; Akl, Elie; Brignardello Petersen, Romina; Emparanza, José; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Roja, Luis; Stirnemann, Jérôme; Irani, Jihad; Hlais, Sani; Mustafa, Reem; Bdair, Fadi; Aly, Abdelrahman; Kristiansen, Annette; Izcovich, Ariel; Ramirez, Anggie; Brozek, Jan; Guyatt, Gordon H.; Sch€unemann, Holger (Elsevier USA, 2018)
      Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. However, some ...
    • Schünemann, Holger; Wiercioch, Wojtek; Brozek, Jan; Etxeandia Ikobaltzeta, Itziar; Mustafa, Reem; Manja, Veena; Brignardello Petersen, Romina; Neumann, Ignacio; Falavigna, Maicon; Alhazzani, Waleed; Santesso, Nancy; Zhang, Yuan; Meerpohl, Jörg; Morgan, Rebecc; Rochwerg, Bram; Darzi, Andrea; Ximenas Rojas, María; Carrasco Labra, Alonso; AlRayees, Zulfa; Riva, John; Bollig, Claudia; Moore, Ainsley; Yepes-Nuñez, Juan; Cuello, Carlos; Waziry, Reem; Akl, Elie A (Elsevier USA, 2017)
      Background Guideline developers can: (1) adopt existing recommendations from others; (2) adapt existing recommendations to their own context; or (3) create recommendations de novo. Monetary and nonmonetary resources, ...
    • Murad, Mohammad Hassan; Montori, Victor M.; Ioannidis, John P A; Jaeschke, Roman; Devereaux, P. J.; Prasad, Kameshwar; Neumann, Ignacio; Carrasco Labra, Alonso; Agoritsas, Thomas; Hatala, Rose; Meade, Maureen O.; Wyer, Peter; Cook, Deborah J.; Guyatt, Gordon H. (American Medical Association, 2014)
      Clinical decisions should be based on the totality of the best evidence and not the results of individual studies. When clinicians apply the results of a systematic review or meta-analysis to patient care, they should start ...
    • Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Garner, Paul; Guyatt, Gordon H.; Sch€unemann, Holger (Elsevier, 2016)
      Objectives: The current format of summary of findings (SoFs) tables for presenting effect estimates and associated quality of evidence improve understanding and assist users finding key information in systematic reviews. ...
    • Kahale, Lara; Diab, Batoul; Brignardello Petersen, Romina; Agarwal, Arnav; Mustafa, Reem; Kwong, Joey; Neumann, Ignacio; Li, Ling; Cruz Lopes, Luciane; Briel, Matthias; Busse, Jason; Lorio, Alfonso; Vandvik, Per Olav; Alexander, Paul; Guyatt, Gordon H.; Akl, Elie (Elsevier, 2018-03-02)
      Objectives: To describe how systematic review authors report and address categories of participants with potential missing outcome data of trial participants. Study Design and Setting: Methodological survey of systematic ...
    • Neumann, Ignacio; Brignardello Petersen, Romina; Wiercioch, Wojtek; Carrasco Labra, Alonso; Cuello, Carlos; Akl, Elie A; Mustafa, Reem; Al-Hazzani, Waleed; Etxeandia-Ikobaltzeta, Itziar; Rojas, María; Falavigna, Maicon; Santesso, Nancy; Brozek, Jan; Iorio, Alf; Alonso-Coello, Pablo; Schünemann, Holger (BioMed Central Ltd., 2016)
      Background: Judgments underlying guideline recommendations are seldom recorded and presented in a systematic fashion. The GRADE Evidence-to-Decision Framework (EtD) offers a transparent way to record and report guideline ...
    • Agoritsas, Thomas; Merglen, Arnaud; Heen, Anja Fog; Kristiansen, Annette; Neumann, Ignacio; Brito, Juan P.; Brignardello Petersen, Romina; Alexander, Paul E.; Rind, David M.; Vandvik, Per O.; Guyatt, Gordon H. (BMJ Publishing Group, 2017)
      Introduction UpToDate is widely used by clinicians worldwide and includes more than 9400 recommendations that apply the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. GRADE guidance ...