Now showing items 1-7 of 7

    • Robles Planells, Claudia; Barrera Ávalos, Carlos; Rojo, Leonel E.; Spencer, Eugenio; Cortez San Martín, Eugenio; Matiacevich, Silvia; Pavez, Jorge; Milla, Luis A.; Navarro, Franco D.; Martínez, Brandon A; Bravo, Francisco J.; Mella, Andrea; Huidobro Toro, Juan Pablo; Fernández, Ricardo; Escobar Álvarez, Alejandro; Acuña Castillo, Claudio (Hindawi, 2020)
      Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
    • Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Burgos, Héctor; Hernández, Alejandro; Constandil, Luis; Ríos, Miguel; Flores, Osvaldo; Puentes, Gustavo; Hernández, Karina; Morgan, Carlos; Valladares Boasi, Luis; Castillo, Amparo; Cofre, Christian; Milla, Luis A.; Sáez-Briones, Patricio; Barra, Rafael (Elsevier B.V., 2019)
      Moderate reduction of dietary protein (from 25% to 8% casein) in pregnant rats, calorically compensated by carbohydrates, gives rise to ‘hidden prenatal malnutrition’ (HPM) in the offspring since it does not alter body and ...
    • Bergeron, Sadie A.; Milla, Luis A.; Villegas, Rosario; Shen, Meng Chieh; Burgess, Shawn M.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma, Verónica (2008)
      The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
    • Feijóo, Carmen G.; Oñate, Maritza G.; Milla, Luis A.; Palma, Verónica A. (2011)
      Despite considerable progress, the mechanisms that control neural progenitor differentiation and behavior, as well as their functional integration into adult neural circuitry, are far from being understood. Given the ...
    • Milla, Luis A.; González-Ramírez, Claudia N.; Palma, Verónica (2012)
      The Sonic Hegdehog/GLI (SHH/GLI) pathway has been extensively studied for its role in developmental and cancer biology. During early embryonic development the SHH pathway is involved mainly in pattern formation, while in ...
    • Villanueva, Andrea A.; Falcón, Paulina; Espinoza, Natalie; Solano, R. Luis; Milla, Luis A.; Hernandez-SanMiguel, Esther; Torres, Vicente A.; Sanchez-Gomez, Pilar; Palma, Verónica (Impact Journals LLC, 2017)
      Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...