Browsing by Author "5bbf342c-57bb-4903-8151-3fba461ecd4a"

Now showing items 1-3 of 3

    • ADAR1-mediated RNA-editing of 3'UTRs in breast cancer 
      Sagredo, Eduardo A.; Blanco, Alejandro; Sagredo, Alfredo I.; Pérez, Paola; Sepúlveda-Hermosilla, Gonzalo; Morales, Fernanda; Müller, Bettina; Verdugo, Ricardo; Marcelain Cubillos, Katherine; Harismendy, Olivier; Armisén, Ricardo (NLM (Medline), 2018)
      RESULTS: We characterized A to G(I) mRNA editing in 81 breast cell lines, showing increased editing at 3'UTR and exonic regions in breast cancer cells compared to immortalized non-malignant cell lines. In addition, tumors ...
    • Expression of SOCS1, SOCS2, and SOCS3 in growth hormone-stimulated skin fibroblasts from children with ... 
      Ocaranza, Paula; Morales, Fernanda; Román, Rossana; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (2012)
      Background/aim: Possible etiologies of idiopathic short stature (ISS) include a range of conditions, some of which may be caused by defects in the modulation of the growth hormone (GH)-signaling pathway. The Janus kinase/signal ...
    • Growth hormone signaling in fibroblasts from newborn boys and prepubertal boys 
      Ocaranza Osses, Paula; Morales, Fernanda; Matamala, Álvaro; Gaete, Ximena; Román, Rossana; Lammoglia, Juan Javier; Cassorla Goluboff, Fernando (Elsevier, 2016-04)
      Background/aim: Responsiveness to GH in target cells is mediated by its receptor, which activates the Janus kinase-2 (JAK2) and STAT5 (signal transducers and activators of transcription 5) leading to the expression of IGF-1 ...