Now showing items 1-4 of 4

    • Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones 

      Pagano, Mariana; Demoro, Bruno; Toloza, Jeannette; Boiani, Lucía; González, Mercedes; Cerecetto, Hugo; Olea Azar, Claudio; Norambuena, Ester; Gambino, Dinorah; Otero, Lucía (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2009-12)
      In the search of new therapeutic tools for the treatment of American Trypanosomiasis, the largest parasitic disease burden in the American continent, three series of novel ruthenium complexes of the formula [RuCl2(HL)(2)], ...
    • Effect of the metal ion on the anti T. cruzi activity and mechanism of action of 5-nitrofuryl-containing thiosemicarbazone metal complexes 

      Cipriani, Micaella; Toloza, Jeannette; Bradford, Lara; Putzu, Eugenia; Vieites, Marisol; Curbelo, Estela; Tomaz, Ana; Garat, Beatriz; Guerrero, Juan; Gancheff, Jorge; Maya Arango, Juan; Olea Azar, Claudio; Gambino, Dinorah; Otero, Lucía (Wiley-VCH Verlag, 2014)
      Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major health problem worldwide. In this work, we report the development of palladium and platinum metal complexes with 5-nitrofuryl-containing ...
    • Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents 

      Vieites, Marisol; Otero, Lucía; Santos, Diego; Toloza, Jeannette; Figueroa, Roberto; Norambuena, Ester; Olea Azar, Claudio; Aguirre, Gabriela; Cerecetto, Hugo; González, Mercedes; Morello Casté, Antonio; Maya Arango, Juan; Garat, Beatriz; Gambino, Dinorah (ELSEVIER SCIENCE INC, 2008-05)
      In the search for new therapeutic tools against Chagas’ disease (American Trypanosomiasis) two series of new platinum(II) complexes with bioactive 5-nitrofuryl containing thiosemicarbazones as ligands were synthesized, ...
    • Water-Soluble Ruthenium Complexes Bearing Activity Against Protozoan Parasites 

      Sarniguet, Cynthia; Toloza, Jeannette; Cipriani, Micaella; Lapier, Michel; Vieites, Marisol; Toledano Magaña, Yanis; García Ramos, Juan Carlos; Ruiz Azuara, Lena; Moreno, Virtudes; Maya Arango, Juan; Olea Azar, Claudio; Gambino, Dinorah; Otero, Lucía (Springer, 2014)
      Parasitic illnesses are major causes of human disease and misery worldwide. Among them, both amebiasis and Chagas disease, caused by the protozoan parasites, Entamoeba histolytica and Trypanosoma cruzi, are responsible ...