Now showing items 1-7 of 7

    • Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano 

      Herrera Videla, Emilio; Reyes, Roberto V.; Giussani, Dino A.; Riquelme González, Raquel; Sanhueza Reinoso, Emilia; Ebensperger Darrouy, Germán; Casanello, Paola; Méndez, Natalia; Ebensperger, Renato; Sepúlveda Kattan, Esteban; Pulgar, Víctor M.; Cabello, Gertrudis; Blanco, Carlos E.; Hanson, Mark A.; Parer, Julian T.; Llanos Mansilla, Jorge (European Society of Cardiology, 2008)
      Aims To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas. Methods and results We used neonatal sheep (Ovis aries) and ...
    • Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress 

      Giussani, Dino A.; Camm, Emily J.; Niu, Youguo; Richter, Hans G.; Blanco, Carlos E.; Gottschalk, Rachel; Blake, E. Zachary; Horder, Katy A.; Thakor, Avnesh S.; Hansell, Jeremy A.; Kane, Andrew D.; Wooding, F. B.Peter; Cross, Christine M.; Herrera, Emilio A. (2012)
      Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding ...
    • Evolving in thin air-Lessons from the llama fetus in the altiplano 

      Llanos Mansilla, Jorge; Riquelme, Raquel A.; Herrera, Emilio A.; Ebensperger Darrouy, Germán; Krause, Bernardo; Reyes, Roberto V.; Sanhueza, Emilia M.; Pulgar, Víctor M.; Behn, Claus; Cabello, Gertrudis; Parer, Julian T.; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A. (2007)
      Compared with lowland species, fetal life for mammalian species whose mothers live in high altitude is demanding. For instance, fetal llamas have to cope with the low fetal arterial PO2 of all species, but also the likely ...
    • Evolving in thin air—Lessons from the llama fetus in the altiplano 

      Llanos Mansilla, Jorge; Riquelme González, Raquel; Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Krause, Bernardo; Reyes, Roberto V.; Sanhueza Reinoso, Emilia; Pulgar, Víctor M.; Behn Thiele, Claus; Cabello, Gertrudis; Parer, Julian T.; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A. (ELSEVIER, 2007)
      Compared with lowland species, fetal life for mammalian species whose mothers live in high altitude is demanding. For instance, fetal llamas have to cope with the lowfetal arterial PO2 of all species, but also the likely ...
    • High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep 

      Herrera Videla, Emilio; Pulgar, Víctor M.; Riquelme González, Raquel; Sanhueza Reinoso, Emilia; Reyes, Roberto V.; Ebensperger Darrouy, Germán; Parer, Julian T.; Valdéz, Enrique A.; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A.; Llanos Mansilla, Jorge (AMER PHYSIOLOGICAL SOC, 2007-06)
      Perinatal exposure to chronic hypoxia induces sustained pulmonary hypertension and structural and functional changes in both pulmonary and systemic vascular beds. The aim of this study was to analyze consequences of ...
    • Vascular reactivity in intrapulmonary arteries of chicken embryos during transition to ex ovo life 

      Villamor, Eduardo; Ruijtenbeek, Karin; Pulgar, Victor; De Mey, Jo G.R.; Blanco, Carlos E. (2002)
      The present study aimed to characterize pulmonary vascular reactivity in the chicken embryo from the last stage of prenatal development and throughout the perinatal period. Isolated intrapulmonary arteries from noninternally ...
    • Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia 

      Sanhueza Reinoso, Emilia; Riquelme González, Raquel; Herrera Videla, Emilio; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A.; Llanos Mansilla, Jorge (AMER PHYSIOLOGICAL SOC, 2005-09)
      The fetal llama responds to hypoxemia, with a marked peripheral vasoconstriction but, unlike the sheep, with little or no increase in cerebral blood flow. We tested the hypothesis that the role of nitric oxide (NO) may be ...