Now showing items 1-10 of 10

    • A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus 

      DebRoy, Sruti; Saldaña, Miguel; Travisany, Dante; Montano, Andrew; Galloway Peña, Jessica; Horstmann, Nicola; Yao, Hui; González Canales, Mauricio; Maass Sepúlveda, Alejandro; Latorre Mora, Mauricio; Shelburne, Samuel (Nature Publishing Group, 2016)
      Catabolite control protein A (CcpA) is a highly conserved, master regulator of carbon source utilization in gram-positive bacteria, but the CcpA regulon remains ill-defined. In this study we aimed to clarify the CcpA regulon ...
    • Complete genome sequence of Microbacterium sp CGR1, bacterium tolerant to wide abiotic conditions isolated from the Atacama Desert 

      Mandakovic Seyler, Dinka; Cabrera, Pablo; Pulgar Tejo, Rodrigo; Maldonado, Jonathan; Aravena, Pamela; Latorre Mora, Mauricio; Cambiazo Ayala, Liliana; González, Mauricio (Elsevier, 2015)
      Microbacterium sp. CGR1 (RGM2230) is an isolate from the Atacama Desert that displays a wide pH, salinity and temperature tolerance. This strain exhibits riboflavin overproducer features and traits for developing an ...
    • Different Transcriptional Responses from Slow and Fast Growth Rate Strains of Listeria monocytogenes Adapted to Low Temperature 

      Cordero Mattos, Ninoska; Maza, Felipe; Navea Pérez, Helen; Aravena, Andrés; Márquez Fontt, Bárbara; Navarrete Wallace, Paola; Figueroa Gronemeyer, Guillermo; González Canales, Mauricio; Latorre Mora, Mauricio; Reyes Jara, Angélica (Frontiers Media, 2016)
      Listeria monocytogenes has become one of the principal foodborne pathogens worldwide. The capacity of this bacterium to grow at low temperatures has opened an interesting field of study in terms of the identification and ...
    • Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease 

      Tallinoa, Savannah; Duffy, Megan; Ralle, Martina; Cortés Burgos, María Paz; Latorre Mora, Mauricio; Burkheada, Jason (Elsevier, 2015)
      Nonalcoholic fatty liver disease (NAFLD) prevalence is increasing worldwide, with the affected US population estimated near 30%. Diet is a recognized risk factor in the NAFLD spectrum, which includes nonalcoholic ...
    • Putative bacterial interactions from metagenomic knowledge with an integrative systems ecology approach 

      Bordron, Philippe; Latorre Mora, Mauricio; Cortés, Maria Paz; González Canales, Mauricio; Thiele, Sven; Siegel, Anne; Maass Sepúlveda, Alejandro; Eveillard, Damien (WILEY-BLACKWELL, 2016)
      Following the trend of studies that investigate microbial ecosystems using different metagenomic techniques, we propose a new integrative systems ecology approach that aims to decipher functional roles within a consortium ...
    • Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency 

      Acuña, Mariana; Castro Fernández, Víctor; Latorre Mora, Mauricio; Castro, Juan; Schuchman, Edward H.; Guixé Leguía, Victoria Cristina; González Canales, Mauricio; Zanlungo, Silvana (Elsevier, 2016)
      Niemann-Pick disease (NPD) type A and B are recessive hereditary disorders caused by deficiency in acid sphingomyelinase (ASM). The p.A1a359Asp mutation has been described in several patients but its functional and structural ...
    • Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ecological factors fostering resilience 

      Mandakovic Seyler, Dinka; Rojas, Claudia; Maldonado, Jonathan; Latorre Mora, Mauricio; Travisany, Dante; Delage, Erwan; Bihouee, Audrey; Jean, Geraldine; Díaz, Francisca; Fernández Gómez, Beatriz; Cabrera, Pablo; Gaete, Alexis; Latorre, Claudio; Gutiérrez, Rodrigo A.; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Liliana; Navarrete, Sergio A.; Eveillard, Damien; González Canales, Mauricio (Nature Publishing Group, 2018)
      Understanding the factors that modulate bacterial community assembly in natural soils is a longstanding challenge in microbial community ecology. In this work, we compared two microbial co-occurrence networks representing ...
    • Synergistic effect of copper and low temperature over Listeria monocytogenes 

      Latorre Mora, Mauricio; Quesille Villalobos, Ana María; Maza, Felipe; Parra, Angel; Reyes Jara, Angélica (Springer, 2015)
      The capacity to grow at low temperatures has allowed Listeria monocytogenes to become one of the primary food pathogens to date, representing a major public health problem worldwide. Several works have described the ...
    • The bioleaching potential of a bacterial consortium 

      Latorre Mora, Mauricio; Cortés Burgos, María Paz; Travisany, Dante; Di Genova, Alex; Budinich Abarca, Marko; Reyes Jara, Angélica; Hödar Quiroga, Christian; González Canales, Mauricio; Parada, Pilar; Bobadilla Fazzini, Roberto; Cambiazo Ayala, Liliana; Maass Sepúlveda, Alejandro (Elsevier, 2016)
      This work presents the molecular foundation of a consortium of five efficient bacteria strains isolated from copper mines currently used in state of the art industrial-scale biotechnology. The strains Acidithiobacillus ...
    • The role of fur in the transcriptional and Iron homeostatic response of Enterococcus faecalis 

      Latorre Mora, Mauricio; Quenti, Daniela; Travisany, Dante; Singh, Kavindra V.; Murray, Barbara E.; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Verónica (Frontiers Media, 2018)
      The ferric uptake regulator (Fur) plays a major role in controlling the expression of iron homeostasis genes in bacterial organisms. In this work, we fully characterized the capacity of Fur to reconfigure the global ...