Browsing by Author "7669abc9-de0a-4699-9636-67d72e4221c7"

Now showing items 1-9 of 9

    • A study about regioisomeric hydroquinones with multiple intramolecular hydrogen bonding 
      Martínez Cifuentes, Maximiliano; Cardona, Wilson; Saitz Barría, Claudio; Weiss López, Boris; Araya Maturana, Ramiro (MDPI AG, 2017)
      A theoretical exploration about hydrogen bonding in a series of synthetic regioisomeric antitumor tricyclic hydroquinones is presented. The stabilization energy for the intramolecular hydrogen bond (IHB) formation in four ...
    • Nanodecoration of single crystals of 5, 11, 17, 23 - tetra - tert- butyl - 25, 27- bis (cyanomethoxy) - 26, ... 
      Moris, S.; Silva, N.; Saitz Barría, Claudio; Jara Vergara, Paul; Chornik, B. (Sociedad Chilena de Química, 2017)
      Single crystals of 1,3-bis(cyanomethoxy)calix[4]arene (1) were grown from Chloroform/Methanol mixture and these were nanodecorated with colloidal gold nanoparticles (AuNps). The single crystals were then characterized by ...
    • Solvent-free microwave-promoted Michael addition of aza-nucleophiles to benzo[b] thiophen-2-yl-2-propenone 
      Pessoa Mahana, Hernán; González, Marcos; González, Marcelo; Pessoa, D.; Araya Maturana, Ramiro; Ron Higuera, Nadia Betsabé; Saitz Barría, Claudio (ARKAT USA INC, 2009)
      A series of Michael adducts (5-11) have been synthesized with good yields under solvent-free microwave conditions. Aliphatic and aromatic amines utilized as Michael donors reacted with 1-(4,7-dimethoxybenzo[b] thiophen-2 ...
    • Spectral and Kinetic Study of 3-Methylquinoxalin-2-ones Photoreduced by Amino Acids: N-Phenylglycine Radical ... 
      Fuente Urrutia, Julio de la; Cañete, Álvaro; Carathanassis, Natalia; Bernazar, Luan; Saitz Barría, Claudio; Díaz Hernández, Dafne (Amer Chemical Society, 2016)
      Transient intermediates were identified in the photoreduction of 3-methylquinoxalin-2-one derivatives by N-phenylglycine, NPG, and N-acetyltryptophan, NAT. For both reductants it can be postulated a sequence of reaction ...
    • Synthesis of 2-benzothienyl carbonyl 4-arylpiperazines as novel delavirdine analogs 
      Pessoa Mahana, Hernán; Acevedo Ramos, Armando Rodrigo; Saitz Barría, Claudio; Araya Maturana, Ramiro; Pessoa, D. (TAYLOR & FRANCIS INC, 2007)
      A novel series of 2-benzothienyl carbonyl arylpiperazines (6a-f) was synthesized as potential HIV nonnucleoside reverse transcriptase inhibitors (NNRTIs). Preparation of the derivatives was performed by reacting benzo[b]thiophene ...
    • Synthesis of conformationally restricted N-{4-[4-(4,7-Dimethoxy-Benzo[b]Thiophene-2-Carbonyl)-1-Piperazin ... 
      Pessoa Mahana, Hernán; González Lira, Christian Guillermo; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (SOC CHILENA QUIMICA, 2009-06)
      New benzothiophene arylpiperazine derivatives 7 (a-1) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by reaction of 1-(4-aminophenyl)-4-[(4 ...
    • Synthesis of Novel p-tert-Butylcalix[4]arene Derivative: Structural Characterization of a Methanol Inclusion ... 
      Moris, Silvana; Galdámez Silva, Antonio; Jara, Paul; Saitz Barría, Claudio (2016)
      A p-tertbutylcalix[4]arene derivative was synthesized from a reaction of the diisothiocyanate p-tertbutylcalix[4]arene, obtaining crystals that were then characterized by mass spectroscopy, Raman spectroscopy, and ...
    • Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines ... 
      Rodríguez Lavado, Julio; Gallardo Garrido, Carlos; Mallea Catalán, Michael; Bustos, Víctor; Osorio, Rodrigo; Hödar Salazar, Martín; Chung, Hery; Araya Maturana, Ramiro; Lorca, Marcos; Pessoa Mahana, C. David; Mella Raipán, Jaime; Saitz Barría, Claudio; Jaque Olmedo, Pablo; Reyes Parada, Miguel; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Hernán (Elsevier, 2020)
      During the last decade, the one drug-one target strategy has resulted to be inefficient in facing diseases with complex ethiology like Alzheimer's disease and many others. In this context, the multitarget paradigm has ...
    • A synthethic overview of new molecules with 5-HT 1A binding affinities 
      Pessoa Mahana, Hernán; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (Bentham Science Publishers, Ltd, 2003)
      The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally telated to arylpiperazine, ...