Browsing by Author "7f690405-7e72-430a-a225-58487ed04908"

Now showing items 1-3 of 3

    • Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor ... 
      González, Alexis E.; Muñoz, Vanessa C.; Cavieres, Viviana A.; Bustamante, Hianara A.; Cornejo, Víctor Hugo; Januário, Yunan C.; González, Ibeth; Hetz Flores, Claudio; Dasilva, Luis L.; Rojas-Fernández, Alejandro; Hay, Ronald T.; Mardones, Gonzalo A.; Burgos, Patricia V. (FASEB, 2017)
      © FASEB. Brain regions affected by Alzheimer disease (AD) displaywell-recognized early neuropathologic features in the endolysosomal and autophagy systems of neurons, including enlargement of endosomal compartments, ...
    • Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion ... 
      Hernández Cáceres, María Paz; Cereceda, Karina; Hernández, Sergio; Li, Ying; Narro, Carla; Rivera, Patricia; Silva, Patricio; Ávalos, Yenniffer; Jara, Claudia; Burgos, Paulina; Toledo Valenzuela, Lilian; Lagos, Pablo; Cifuentes Araneda, Flavia; Pérez Leighton, Claudio; Bertocchi, Cristina; Clegg, Deborah J.; Criollo Céspedes, Alfredo; Tapia Rojas, Cheril; Burgos, Patricia V.; Morselli, Eugenia (Taylor & Francis, 2020)
      High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed ...
    • The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts ... 
      Arriagada, Cecilia; Luchsinger, Charlotte; González, Alexis E.; Schwenke, Tomás; Arriagada, Gloria; Folch, Hugo; Ehrenfeld, Pamela; Burgos, Patricia V.; Mardones, Gonzalo A. (Public Library of Science, 2019)
      Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown. ...