Browsing by Author "846c6c7f-3921-4cc4-8fde-299e429cea9a"

Now showing items 1-4 of 4

    • CK2 functionally interacts with AKT/PKB to promote the β-catenin- dependent expression of survivin and ... 
      Ponce, Daniela P.; Yefi, Roger; Cabello, Pablo; Maturana, Jose L.; Niechi, Ignacio; Silva, Eduardo; Galindo, Mario; Antonelli, Marcelo; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo; Tapia, Julio C. (2011)
      β-Catenin is crucial in the canonical Wnt signaling pathway. This pathway is up-regulated by CK2 which is associated with an enhanced expression of the antiapoptotic protein survivin, although the underlying molecular ...
    • Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of β-catenin transcriptional ... 
      Ponce, Daniela P.; Maturana, Jose L.; Cabello, Pablo; Yefi, Roger; Niechi, Ignacio; Silva, Eduardo; Armisen Yáñez, Ricardo; Galindo, Mario; Antonelli, Marcelo; Tapia, Julio C. (2011)
      β-Catenin is a key protein in the canonical Wnt signaling pathway and in many cancers alterations in transcriptional activity of its components are observed. This pathway is up-regulated by the protein kinase CK2, but the ...
    • Protein kinase CK2 promotes cancer cell viability via up-regulation of cyclooxygenase-2 expression and ... 
      Yefi, Roger; Ponce, Daniela P.; Niechi, Ignacio; Silva, Eduardo; Cabello, Pablo; Rodriguez, Diego A.; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo; Quest, Andrew F. G.; Tapia, Julio C. (2011)
      Augmented expression of protein kinase CK2 is associated with hyperproliferation and resistance to apoptosis in cancer cells. Effects of CK2 are at least partially linked to signaling via the Wnt/β-catenin pathway, which ...
    • The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition ... 
      Contreras, Hector R.; Ledezma, Rodrigo A.; Vergara, Jorge; Cifuentes, Federico; Barra, Cristina; Cabello, Pablo; Gallegos, Ivan; Morales, Bernardo; Huidobro, Christian; Castellón, Enrique A. (2010)
      The epithelial-mesenchymal transition (EMT) is considered a key step in tumor progression, where the invasive cancer cells change from epithelial to mesenchymal phenotype. During this process, a decrease or loss in adhesion ...