Browsing by Author "912d3917-cc5b-4373-8278-56d894ba2a6e"

Now showing items 1-14 of 14

    • 46,XX/SRY-negative true hermaphrodite 
      Parada-Bustamante, Alexis; Ríos, Rafael; Ebensperger, Mauricio; Lardone, María Cecilia; Piottante, Antonio; Castro, Andrea (Elsevier Inc., 2010)
      Objective: To describe genetic evaluation and response to surgery and letrozole therapy of a 46,XX/SRY-negative true hermaphrodite. Design: Case report. Setting: University Medical Center. Patient(s): Nineteen-year-old ...
    • Absence of Y chromosome microdeletions in patients with cryptorchidism and hypospadias 
      Castro, Andrea; Codner Dujovne, Ethel; Kaune, Heidy; López, Patricia; Vantman, David; Cassorla Goluboff, Fernando (Freund Publishing House Ltd, 2004)
      Microdeletions of the Y chromosome have been observed in some patients with cryptorchidism and severe defects of spermatogenesis. We investigated whether microdeletions of the Y chromosome may be present in patients with ...
    • Androgen receptor CAG and GGN polymorphisms in boys with isolated hypospadias 
      Parada Bustamante, Alexis; Lardone, María Cecilia; Madariaga, Marcia; Johnson, María Cecilia; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Castro, Andrea (2012)
      Background: The etiology of hypospadias is multifactorial. Abnormal androgenic secretion and/or action during the development of external genitalia may be involved in the etiology of this congenital malformation. This study ...
    • Androgen receptor gene CAG and GGN repeat polymorphisms in Chilean men with primary severe spermatogenic failure 
      Castro-Nallar, Eduardo; Bacallao, Ketty; Parada-Bustamante, Alexis; Lardone, María C.; López, Patricia V.; Madariaga, Marcia; Valdevenito, Raúl; Piottante, Antonio; Ebensperger, Mauricio; Castro, Andrea (2010)
      There is ample documentation supporting the fact that androgens are required for normal spermatogenesis. A minority of infertile men have abnormal testosterone blood levels or mild androgen receptor mutations. We investigated ...
    • Androgen receptor gene cag repeat polymorphism in girls with high DHEAS: association with pubertal events ... 
      Lardone, María Cecilia; Castro, Andrea; Ortiz, Eliana; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Mericq, Verónica (Karger, 2017)
    • AZFc partial deletions in Chilean men with severe spermatogenic failure 
      Lardone, María C.; Parodi, Daniela A.; Ebensperger, Mauricio; Peñaloza, Paulina; Bahamondes Cornejo, Valeria Cristina; Valdevenito, Raúl; Pommer, Ricardo; Castro, Andrea (2007)
      Objective: To determine the prevalence of AZFc subdeletions in infertile Chilean men with severe spermatogenic impairment. Design: Prospective analysis. Setting: University infertility clinic. Patient(s): Ninety-five ...
    • Greater prevalence of Y chromosome Q1a3a haplogroup in Y-microdeleted Chilean men: a case-control study. 
      Lardone, María C.; Marengo, Altinay; Parada Bustamante, Alexis; Cifuentes, Lucía; Piottante, Antonio; Ebensperger, Mauricio; Valdevenito, Raúl; Castro, Andrea (2013)
      To determine the prevalence of South Amerindian Y chromosome in Chilean patients with spermatogenic failure and their association with classical and/or AZFc-partial Y chromosome deletions. We studied 400 men, 218 with ...
    • Luteal leukocytes are modulators of the steroidogenic process of human mid-luteal cells 
      Castro, Andrea; Castro, Olga; Troncoso, José Luis; Kohen Skop, Paulina; Simon, Carlos; Vega Blanco, María Margarita; Devoto, Luigi (Oxford University Press, 1998)
      Flow cytometry analysis of luteal cells revealed that an important proportion of these cells are leukocytes. The percentage of leukocytes was higher in the early (42 ± 4) and late (35 ± 3) luteal phases than in the mid-luteal ...
    • Lymphocyte adhesion to endothelium derived from human lymphoid tissue 
      Castro, Andrea; Bono Merino, María Rosa; Simon, Valeska; Rosemblatt Silber, Mario César (Elsevier GmbH, 1996)
      The development of an efficient immune response depends on the capacity of antigen-specific lymphocytes to migrate into secondary lymphoid organs. The first step in the process of lymphocyte extravasation involves lymphocyte ...
    • MiR-155 and miR-122 expression of spermatozoa in obese subjects 
      López, Paulina; Castro, Andrea; Florez, M.; Miranda, Karen; Aranda, Pilar; Sánchez-González, Cristina; Llopis, Juan; Arredondo Olguin, Miguel Armando (Frontiers Media S.A., 2018-05-29)
      Obesity is characterized by mild chronic inflammation that is linked with impaired iron homeostasis. Studies in human and murine show that there is a transgenerational epigenetic inheritance via the gametes in obesity; ...
    • Partial-AZFc deletions in Chilean men with primary spermatogenic impairment: gene dosage and Y-chromosome ... 
      Lardone, María Cecilia; Ortega, Victoria; Ortiz, Eliana; Flórez, M.; Piottante, Antonio; Ebensperger, Mauricio; Flores, Sandra; Pezo, Patricio; Orellana, Michael; Moraga, Mauricio; Castro, Andrea (Springer, 2020)
      Purpose To investigate the association of partial-AZFc deletions in Chilean men with primary spermatogenic failure and their testicular histopathological phenotypes, analyzing the contribution ofDAZdosage,CDY1copies, and ...
    • Presence of angiotensin II and expression of angiotensin II type-2 receptor in human fallopian tube 
      Johnson, M. Cecilia; Castro, Andrea; Troncoso, José Luis; Vantman, David; Devoto, Luigi; Vega Blanco, María Margarita (1998)
      Objective: To determine the presence of angiotensin II and angiotensin II type-2 receptor subtype messenger RNA (mRNA) in human fallopian tube. Design: Frozen fallopian tubes were used for all studies. Setting: Procedures ...
    • Role of nitric oxide and bcl-2 family genes in the regulation of human endometrial apoptosis 
      Castro, Andrea; Johnson, María Cecilia; Anido, Mabel; Cortinez, Armando; Gabler Neale, Fernando; Vega Blanco, María Margarita (2002)
      Objective: To investigate the role of nitric oxide (NO) and death regulatory genes, bcl-2 and bax, in human endometria apoptosis.Design: Expression of bcl-2, bax, NO synthases (NOS), and the apoptotic effect of L-arginine ...
    • Role of the Androgen Receptor Gene CAG Repeat Polymorphism on the Sequence of Pubertal Events and Adiposity ... 
      Lardone, María Cecilia; Castro, Andrea; Pereira, Ana; Corvalán Aguilar, Camila; Ortíz, Eliana; Mericq, Verónica (Elsevier USA, 2019)
      Study Objective: The androgen receptor (AR) harbors a variable repeat number of glutamine residues codified by (CAG)n, which seems to inversely affect AR transcriptional activity. We assessed whether (CAG)n affects the ...