Browsing by Author "965fbcc9-7b13-4fbb-898c-49a93888a2bf"

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    • 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors 
      Lühr, Susan; Vilches Herrera, Marcelo; Fierro, Angélica; Ramsay, Rona R.; Edmondson, Dale E.; Reyes Parada, Miguel; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio (2010)
      2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
    • Why p-OMe- and p-Cl-beta-Methylphenethylamines Display Distinct Activities uponMAO-B Binding 
      Fierro, Angélica; Edmondson, Dale E.; Celis Barros, Cristian; Rebolledo Fuentes, Marco; Zapata Torres, Gerald (Public Library Science, 2016)
      Despite their structural and chemical commonalities, p-chloro-beta-methylphenethylamine and p-methoxy-beta-methylphenethylamine display distinct inhibitory and substrate activities upon MAO-B binding. Density Functional ...