Now showing items 1-6 of 6

    • A two-step method for the preparation of homochiral cathinones 

      Osorio Olivares, Mauricio; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Baggio, Ricardo; Muñoz Acevedo, Juan Carlos (Elsevier Science Ltd., 2003-03-12)
      Abstract—A simple method for the preparation of homochiral ring-substituted 1-aryl-2-aminopropanones 2 (‘cathinones’) is described, involving initial Friedel–Crafts acylation of aromatics with (S)- or (R)-N-trifluoroacetylalanyl ...
    • Corrigendum to “Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome” [Int. J. Med. Microbiol. 304 (3–4) (2014) 384–392] 

      Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriel; Vidal Alvarez, Roberto; Hermoso Ramello, Marcela (ELSEVIER, 2015)
    • Escherichia coli isolates from inflammatory bowel diseases patientssurvive in macrophages and activate NLRP3 inflammasome 

      Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriela; Vidal Ávarez, Roberto; Hermoso Ramello, Marcela (Elsevier, 2014)
      Crohn’s disease (CD) is a multifactorial pathology associated with the presence of adherent-invasiveEscherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in otherintestinal pathologies ...
    • Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: Insights from molecular modeling studies 

      Fierro, Angélica; Osorio Olivares, Mauricio; Cassels Niven, Bruce; Edmondson, Dale E.; Sepúlveda Boza, Silvia; Reyes Parada, Miguel (Elsevier Ltd., 2007-05-22)
      Abstract—Four enantiomerically pure (S)-4-alkylthioamphetamine derivatives were evaluated as monoamine oxidase (MAO) inhibitors using the human and rat isoforms of the enzyme. Molecular dockings were performed in order ...
    • MAO inhibition by arylisopropylamines: the effect of oxygen substituents at the b-position 

      Osorio Olivares, Mauricio; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Fierro, Angélica (Elsevier Ltd., 2004-05-26)
      Abstract—Twenty-nine arylisopropylamines, substituted at the b-position of their side chain by an oxo, hydroxy, or methoxy group, were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives (‘cathinones’) ...
    • Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024 

      Ferreccio, Catterina; Roa, Juan Carlos; Bambs, Claudia; Vives, Alejandra; Corvalán, Alejandro H.; Cortés, Sandra; Foerster, Claudia; Acevedo, Johanna; Huidobro, Andrea; Passi, Alvaro; Toro, Pablo; Covacevich, Yerko; Cruz, Rolando de la; Koshiol, Jill; Olivares, Mauricio; Miquel, Juan Francisco; Cruz, Francisco; Silva, Raúl; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Castro, Pablo F.; Lavandero González, Sergio (BioMed Central, 2016)
      Background: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina's population ...