Browsing by Author "985eef02-22bd-45b6-b4c8-3c06156ce035"

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    • Depolarization of skeletal muscle cells induces phosphorylation of cAMP response element binding protein ... 
      Cárdenas, César; Müller, Marioly; Jaimovich Pérez, Enrique; Pérez, Francisco; Buchuk, Diego; Quest, Andrew F. G.; Carrasco, Maria Angélica (2004)
      Membrane depolarization of skeletal muscle cells induces slow inositol trisphosphate-mediated calcium signals that regulate the activity of transcription factors such as the cAMP-response element-binding protein (CREB), ...
    • Mitochondria and calcium regulation as basis of neurodegeneration associated with aging 
      Müller, Marioly; Ahumada-Castro, Ulises; Sanhueza, Mario; González Billault, Christian; Court, Felipe A.; Cárdenas, César (Frontiers Media S.A., 2018)
      © 2018 Müller, Ahumada-Castro, Sanhueza, Gonzalez-Billault, Court and Cárdenas.Age is the main risk factor for the onset of neurodegenerative diseases. A decline of mitochondrial function has been observed in several ...
    • Selective Vulnerability of Cancer Cells by Inhibition of Ca2+ Transfer from Endoplasmic Reticulum to Mitochondria 
      Cárdenas, César; Müller, Marioly; McNeal, Andrew; Lovy, Alenka; Jaňa, Fabian; Bustos, Galdo; Urra, Felix; Smith, Natalia; Molgó, Jordi; Diehl, J. Alan; Ridky, Todd W.; Foskett, J. Kevin (Elsevier B.V., 2016)
      © 2016 The Authors.In the absence of low-level ER-to-mitochondrial Ca2+ transfer, ATP levels fall, and AMPK-dependent, mTOR-independent autophagy is induced as an essential survival mechanism in many cell types. Here, we ...