Now showing items 1-14 of 14

    • (2S,R-S)-6-Phenyl-1-(p-tolylsulfinyl)-hexa-3(E),5(E)-dien-2-ol 

      Donoso Tauda, Oscar; Escobar, Carlos A.; Araya Maturana, Ramiro; Vega, Andrés (BLACKWELL PUBLISHING, 2006-10)
      The molecule of the title compound, C19H20O2S, corresponds to a chiral sulfinyldienol with two stereogenic centres, viz. the C atom susbtituted by the hydroxy group and the sulfinyl S atom. The molecule displays a V-shape ...
    • Chalcone-induced apoptosis through caspase-dependent intrinsic pathways in human hepatocellular carcinoma cells 

      Ramirez-Tagle, Rodrigo; Escobar, Carlos A.; Romero, Valentina; Montorfano, Ignacio; Armisén, Ricardo; Borgna, Vincenzo; Jeldes, Emanuel; Pizarro, Luis; Simon, Felipe; Echeverria, Cesar (MDPI AG, 2016)
      © 2016 by the authors; licensee MDPI, Basel, Switzerland. Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide. Chemoprevention of HCC can be achieved through the use of natural or synthetic ...
    • Chemical composition of precloacal secretions of two Liolaemus fabiani populations: Are they different? 

      Escobar, Claudio M.; Escobar, Carlos A.; Labra, Antonieta; Niemeyer, Hermann M. (2003)
      The chemical composition of secretions of precloacal pores from two populations of the lizard Liolaemusfabiani (Puilar and Punta-Brava) were compared. This is an endemic species from the Atacama Salt Flat (26°46'S 68° 14'W; ...
    • Correlating experimental electrochemistry and theoretical calculations in 2 '-hydroxy chalcones: the role of the intramolecular hydrogen bond 

      Martínez Cifuentes, Maximiliano; Salazar, Ricardo; Escobar, Carlos A.; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Royal Soc Chemistry, 2015)
      In this work we present a study on the molecular structure and electrochemical behavior of a series of methoxylated 2'-hydroxychalcones, whose antitumor activity has been previously described. Cyclic voltammetry was used ...
    • (E)-3-(2,3-dimethoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one 

      Escobar, Carlos A.; Vega, Andrés; Sicker, Dieter; Ibañez, Andrés (WILEY-BLACKWELL PUBLISHING, 2008-09)
      The molecular conformation of the title compound, C18H18O5, is stabilized by a strong intramolecular hydrogen bond between the hydroxyl and carbonyl groups. The C = C double bond displays an E configuration while the ...
    • Evaluation of DIMBOA analogs as antifeedants and antibiotics towards the aphid Sitobion avenae in artificial diets 

      Escobar, Carlos A.; Sicker, Dieter; Niemeyer, Hermann M. (Kluwer Academic/Plenum Publishers, 1999)
      A total of 25 compounds including benzoxazinones, benzoxazolinones, and N-glyoxylamide derivatives were tested as antifeedants and antibiotics towards the aphid Sitobion avenae in diet bioassays. The antifeedant and mortality ...
    • Five bicyclo-[3.3.0]octa-2,6-dienes 

      Vega, Andrés; Donoso-Tauda, Oscar; Ibãez, Andres; Escobar, Carlos A. (2008)
      A series of five compounds containing the bicyclo-[3.3.0]octa-2,6-diene skeleton are described, namely tetra-methyl cis,cis-3,7-dihydroxy-bicyclo-[3.3. 0]octa-2,6-diene-2,4-exo,6,8-exo-tetracarboxyl-ate, C16H18O10, (I), ...
    • Gold nanoparticles for photothermally controlled drug release 

      Guerrero, Ariel R.; Hassan, Natalia; Escobar, Carlos A.; Albericio, Fernando; Kogan Bocian, Marcelo; Araya, Eyleen (Future Medicine Ltd., 2014)
      © 2014 Future Medicine Ltd. In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is ...
    • Potential of hydroxamic acids in breeding for aphid resistance in wheat 

      Escobar, Carlos; Niemeyer, Hermann (1993)
      Swedish wheats were analysed at the seedling stage for hydroxamic acids (Hx), a family of natural aphid resistance factors. Analysis comprised the historical development from old landraces to modem cultivars, and included ...
    • Sensing immobilized molecules of streptavidin on a silicon surface by maldi-tof mass spectrometry and fluorescence microscopy 

      Araya, Eyleen; Kogan Bocian, Marcelo; Guell, Aleix G.; Escobar, Carlos A.; Sanz, Fausto (2014)
      A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin. Cleavage of an N-(ω- undecylenyl)-phthalimide covered surface using hidrazine yields an amino ...
    • Sources of pheromones in the lizard Liolaemus tenuis 

      Labra, Antonieta; Escobar, Carlos A.; Aguilar, Paz M.; Niemeyer, Hermann M. (Sociedad de Biologia de Chile, 2002)
      Experimental tests were conducted with the lizard Liolaemus tenuis (Tropiduridae), to determine the potential sources of pheromones used in its chemical communication, centered in the phenomenon of self-recognition. During ...
    • Structural antitumoral activity relationships of synthetic chalcones 

      Echeverría, César; Santibáñez, Juan Francisco; Donoso Tauda, Óscar; Escobar, Carlos A.; Ramírez Tagle, Rodrigo (2009)
      Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2'-hydroxychalcones resulted in apoptosis induction ...
    • Study by fluorescence of calix[4]arenes bearing heterocycles with anions: Highly selective detection of iodide 

      Gómez Machuca, Horacio Exequiel; Quiroga Campano, Cinthia del Rosario; Jullian Matthaei, Carolina; De la Fuente, Julio; Pessoa Mahana, Hernán; Escobar, Carlos A.; Dobado, José A.; Saitz Barría, Claudio (Kluwer Academic Publishers, 2015)
      © Springer Science+Business Media Dordrecht 2014. The present work describes a study of complexation efficiency of calix[4]arenes bearing benzoimidazolyl, benzothiazolyl, and benzoxazolyl heterocycles (5-7) towards several ...
    • Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions 

      Escobar, Carlos A.; Donoso Tauda, Oscar; Araya Maturana, Ramiro; Sicker, Dieter (2009)
      1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave ...