Browsing by Author "XX639405"

Now showing items 1-8 of 8

    • Gonyautoxin: New treatment for healing acute and chronic anal fissures 
      Garrido Crovetto, Rogelio; Lagos Wilson, Néstor; Lattes, Karinna; Abedrapo Moreira, Mario; Bocic Alvarez, Gunther; Cuneo, Aldo; Chiong, Hector; Jensen Benítez, Christian; Azolas Marcos, Rodrigo; Henríquez, Ana; García, Carlos (LIPPINCOTT WILLIAMS & WILKINS, 2005-02)
      PURPOSE: The mayor symptoms of chronic anal fissure are permanent pain, intense pain during defecation that lasts for hours, blood in the stools, and sphincter cramps. It is subsequent to formation of fibrosis infiltrate ...
    • Highly Toxic Microcystis aeruginosa Strain, Isolated from Sao Paulo—Brazil, Produce Hepatotoxins and Paralytic ... 
      Sant'Anna, Célia L.; Carvalho, Luciana R. de; Fiore, Marli F.; Silva-Stenico, María Estela; Lorenzi, Adriana S.; Ríos, Fernanda R.; Konno, Katsuhiro; García, Carlos; Lagos Wilson, Néstor (Springer, 2011)
      While evaluating several laboratory-cultured cyanobacteria strains for the presence of paralytic shellfish poison neurotoxins, the hydrophilic extract of Microcystis aeruginosa strain SPC777—isolated from Billings’s ...
    • In vivo blockade of ovarian sympathetic activity by neosaxitoxin prevents polycystic ovary in rats 
      Campos, Miguel del; Lagos Wilson, Néstor; Lara Peñaloza, Hernán (Biocientífica, 2020)
      A high sympathetic tone is observed in the development and maintenance of the polycystic ovary (PCO) phenotype in rats. Neosaxitoxin (NeoSTX) specifically blocks neuronal voltage-dependent Na+ channels, and we studied ...
    • Lens Major Intrinsic Protein (MIP) Promotes Adhesion When Reconstituted into Large Unilamellar Liposomes 
      Michea Acevedo, Luis; Fuente Vera, Milton de la; Lagos Wilson, Néstor (1994)
      The vertebrate lens behaves like a syncytium, and it is formed mainly by cells called lens fibers. Between the fibers are extensive networks of membrane junctions. The major intrinsic protein (MIP) constitutes about ...
    • Neosaxitoxin inhibits the expression of inflammation markers of the M1 Phenotype in macrophages 
      Montero Sepúlveda, María Cecilia; Campo, Miguel del; Bono Merino, María Rosa; Simon Zegers, María Valeska; Guerrero Peralta, Julia; Lagos Wilson, Néstor (MDPI, 2020)
      Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide ...
    • Route of metabolization and detoxication of paralytic shellfish toxins in humans 
      García, Carlos; Barriga, Andrés; Díaz Jeraldo, Juan; Lagos, Marcelo; Lagos Wilson, Néstor (ELSEVIER, 2010)
      Paralytic shellfish toxins (PST) are a collection of over 26 structurally related imidazoline guanidinium derivatives produced by marine dinoflagellates and freshwater cyanobacteria. Glucuronidation of drugs by ...
    • Seasonal variability of Dinophysis spp. and Protoceratium reticulatum associated to lipophilic shellfish ... 
      Alves de Souza, Catharina; Varela, Daniel; Contreras, Cristóbal; Iglesia, Pablo de la; Fernández, Pamela; Hipp, Byron; Hernández, Cristina; Riobó, Pilar; Reguera, Beatriz; Franco, José M.; Diogene, Jorge; García Carrasco, Carlos Alfredo; Lagos Wilson, Néstor (Elsevier, 2014)
      The fine scale vertical distribution of Dinophysis spp. and Protoceratium reticulatum (potential producers of lipophilic shellfish toxins, LSTs) and its relation with LSTs in shellfish was studied in Reloncaví fjord, a ...
    • Treatment of chronic anal fissure by gonyautoxin 
      Garrido Crovetto, Rogelio; Lagos Wilson, Néstor; Lagos, M.; Rodríguez Navarro, Alberto J.; García, Carlos; Truan, D.; Henríquez, Ana (2007)
      Objective The use of gonyautoxin has been reported to be safe and effective in healing acute and chronic anal fissures. This study was designed to show better efficacy in healing patients with chronic anal fissure by ...