Browsing by Author "b321cdcb-ffd4-4ba1-bf38-46561c32ea96"
Now showing items 1-5 of 5
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McDonald, Tanya S.; Carrasco Pozo, Catalina; Hodson, Mark P.; Borges, Karin (Soc Neuroscience, 2017)Temporal lobe epilepsy is a common form of adult epilepsy and shows high resistance to treatment. Increasing evidence has suggested that metabolic dysfunction contributes to the development of seizures, with previous studies ...
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Tan, Kah Ni; Hood, Rebecca; Warren, Kirby; Pepperall, Debbie; Carrasco Pozo, Catalina; Manzanero, Silvia; Borges, Karin; Spratt, Neil J. (Elsevier Ireland Ltd, 2018)© 2018 Elsevier B.V. Triheptanoin, the medium-chain triglyceride of heptanoate, has been shown to be anticonvulsant and neuroprotective in several neurological disorders. In the gastrointestinal tract, triheptanoin is ...
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Carrasco Pozo, Catalina; Tan, Kah Ni; Gotteland, Martin; Borges, Karin (Hindawi Limited, 2017)© 2017 Catalina Carrasco-Pozo et al. Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, leading to an impaired insulin secretory response to glucose. This study aimed to determine the protective ...
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Carrasco Pozo, Catalina; Tan, Kah Ni; Reyes Farías, Marjorie; De la Jara, Nicole; Ngo, Shyuan Thieu; García Díaz, Diego; Llanos Vidal, Paola; Cires, María José; Borges, Karin (Elsevier, 2016)Studying rats fed high cholesterol diet and a pancreatic beta-cell line (Min6), we aimed to determine the mechanisms by which quercetin protects against cholesterol-induced pancreatic beta-cell dysfunction and impairments ...
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Tan, Kah Ni; Simmons, David; Carrasco Pozo, Catalina; Borges, Karin (Wiley, 2018)Triheptanoin, the triglyceride of heptanoate, is anaplerotic (refills deficient tricarboxylic acid cycle intermediates) via the propionyl-CoA carboxylase pathway. It has been shown to be neuroprotective and anticonvulsant ...