Browsing by Author "b36a9e2d-7b86-4e70-b57c-d82d740b82b9"

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    • A Flap Endonuclease (TcFEN1) Is Involved in Trypanosoma cruzi Cell Proliferation, DNA Repair, and Parasite Survival 
      Ponce, Iván; Aldunate, Carmen; Valenzuela, Lucía; Sepúlveda Contreras, Sofía; Garrido, Gilda; Kemmerling Weis, Ulrike; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel (Wiley, 2017)
      FLAP endonucleases (FEN) are involved both in DNA replication and repair by processing DNA intermediaries presenting a nucleotide flap using its phosphodiesterase activity. In spite of these important functions in DNA ...
    • Characterization of Trypanosoma cruzi MutY DNA glycosylase ortholog and its role in oxidative stress response 
      Kunrath Lima, Marianna; Marçal Repolês, Bruno; Alves, Ceres Luciana; Furtado, Carolina; Andrade Rajao, Matheus; Macedo, Andrea Mara; Franco, Gloria Regina; Junho Pena, Sergio Danilo; Valenzuela, Lucía; Wisnovsky, Simon; Kelley, Shana O.; Galanti Garrone, Norbel; Cabrera Vallejos, Gonzalo; Machado, Carlos Renato (Elsevier, 2017)
      Trypanosoma cruzi is a protozoan parasite and the causative agent of Chagas disease. Like most living organisms, it is susceptible to oxidative stress, and must adapt to distinct environments. Hence, DNA repair is essential ...
    • Differential infectivity of two Trypanosoma cruzi strains in placental cells and tissue 
      Medina, Lisvaneth; Castillo, Christian; Liempi, Ana; Herbach, Mathias; Cabrera, Gonzalo; Valenzuela, Lucía; Galanti Garrone, Norbel; de los Angeles Curto, María; Schijman, Alejandro G.; Kemmerling Weis, Ulrike (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Congenital Chagas disease, caused by Trypanosoma cruzi (T. cruzi), has become epidemiologically relevant. The probability of congenital transmission depends on the maternal and developing fetal/newborn ...
    • Expression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA Glycosylase 
      Ormeno, Fernando; Barrientos, Camila; Ramírez, Santiago; Ponce, Iván; Valenzuela, Lucía; Sepúlveda, Sofía; Bitar, Maina; Ulrike Kemmerling, Weis; Machado, Carlos Renato; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel (Public Library Science, 2016-06-10)
      Trypanosoma cruzi, the etiological agent of Chagas' disease, presents three cellular forms (trypomastigotes, epimastigotes and amastigotes), all of which are submitted to oxidative species in its hosts. However, T. cruzi ...
    • Parasitosis and irritable bowel syndrome Parasitosis y síndrome de intestino irritable 
      Ibarra, Catalina; Herrera, Valentina; Pérez de Arce Oñate, Edith Paola; Gil, Luis Carlos; Madrid, Ana María; Valenzuela, Lucía; Beltrán, Caroll J. (Sociedad Chilena de Infectologia, 2016)
      © 2016, Sociedad Chilena de Infectologia. All rights reserved.Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract characterised by multifactorial aetiology. In IBS physiopathology are ...