Now showing items 1-4 of 4

    • Michels, Karin B.; Keller, Kristen; Pereira, Ana; Kim, Claire E.; Santos, José L.; Shepherd, John A.; Corvalán, Camila; Binder, Alexandra M. (BMC, 2020)
      Background Systemic inflammation may play a role in shaping breast composition, one of the strongest risk factors for breast cancer. Pubertal development presents a critical window of breast tissue susceptibility to exogenous ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Calafat, Antonia M.; Ye, Xiaoyun; Mericq, Verónica; Pereira Scalabrino, Ana; Michels, Karin B. (BIOMED Central Ltd., 2018)
      Background: The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposure ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Binder, Alexandra M.; Stiemsma, Leah T.; Keller, Kristen; Van Otterdijk, Sanne D.; Mericq, Verónica; Pereira, Ana; Santos, José Luis; Shepherd, John; Michels, Karin B. (BioMed Central Ltd., 2018)
      © 2018 The Author(s). Background: Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The influence of epigenetic regulation of ...