Now showing items 1-3 of 3

    • Childhood and adolescent phenol and phthalate exposure and the age of menarche in Latina girls 

      Binder, Alexandra M.; Corvalán Aguilar, Camila; Calafat, Antonia M.; Ye, Xiaoyun; Mericq, Verónica; Pereira Scalabrino, Ana; Michels, Karin B. (BIOMED Central Ltd., 2018)
      Background: The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposure ...
    • Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls 

      Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Inverse association between estrogen receptor-α DNA methylation and breast composition in adolescent Chilean girls 

      Binder, Alexandra M.; Stiemsma, Leah T.; Keller, Kristen; Van Otterdijk, Sanne D.; Mericq, Verónica; Pereira, Ana; Santos, José Luis; Shepherd, John; Michels, Karin B. (BioMed Central Ltd., 2018)
      © 2018 The Author(s). Background: Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The influence of epigenetic regulation of ...