Now showing items 1-5 of 5

    • Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Ma (2011)
      Objective Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Ormeño, Fernando; Hormazábal, Juan; Moreno, José; Riquelme, Felipe; Ríos, Javiera; Criollo Céspedes, Alfredo; Albornoz, Amelina; Alfaro, Iván E.; Budini, Mauricio (Frontiers Media, 2020)
      TAR DNA binding protein 43 kDa (TDP-43) is a ribonuclear protein regulating many aspects of RNA metabolism. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD) are fatal neurodegenerative ...
    • Alfaro, Iván E.; Albornoz, Amelina; Molina, Alfredo; Moreno, José; Cordero, Karina; Criollo Céspedes, Alfredo; Budini, Mauricio (Frontiers Media, 2019)
      Chaperone Mediated Autophagy (CMA) is a lysosomal-dependent protein degradation pathway. At least 30% of cytosolic proteins can be degraded by this process. The two major protein players of CMA are LAMP-2A and HSC70. While ...
    • Ewert, Patricia; Aguilera, Sergio; Alliende, Cecilia; Kwon, Yoon Jeoung; Albornoz, Amelina; Molina, Claudio; Urzúa, Ulises; Quest, Andrew F. G.; Olea, Nancy; Pérez, Paola; Castro, Isabel; Barrera, María José; Romo, Rafael; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Mar (2010)
      Objective. Disorganization of acinar cell apical microvilli and the presence of stromal collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is impaired in patients with Sjögren's ...
    • Albornoz, Amelina; Yáñez López, José; Foerster, Claudia; Aguirre, Celeste; Pereiro, Luisa; Burzio, Verónica; Moraga, Mauricio; Reyes, Ariel E.; Antonelli, Marcelo (Society of Biology of Chile, 2007)
      Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described ...