Now showing items 1-6 of 6

    • Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials 

      Kasenda, Benjamín; von Elm, Erik; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari; Neumann, Ignacio; Carrasco Labra, Raúl; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martín A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Public Library Science, 2016)
      Background Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
    • Completion and Publication Rates of Randomized Controlled Trials in Surgery An Empirical Study 

      Rosenthal, Rachel; Kasenda, Benjamin; Dell-Kuster, Salome; Elm, Erik von; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Sohail, Mulla; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Olu, Kelechi K.; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Bradley C., Johnston; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Lippicott Williams & Wilkins, 2015)
      Objective: To investigate the prevalence of discontinuation and nonpublication of surgical versus medical randomized controlled trials (RCTs) and to explore risk factors for discontinuation and nonpublication of surgical ...
    • Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study 

      Schandelmaier, Stefan; Elm, Erik von; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Lamontagne, Francois; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Sun, Xin; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Cook, Deborah J.; Meade, Maureen O.; Bucher, Heiner C.; Kasenda, Benjamin; Briel, Matthias (Lippicott Williams & Wilkins, 2016)
      Objectives: Randomized clinical trials that enroll patients in critical or emergency care (acute care) setting are challenging because of narrow time windows for recruitment and the inability of many patients to provide ...
    • Prevalence, Characteristics, and Publication of Discontinued Randomized Trials 

      Kasenda, Benjamin; Von Elm, Erik; You, John; Blümle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Schandelmaier, Stefan; Xin, Sun; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (American Medical Association., 2014)
      IMPORTANCE The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. OBJECTIVES To ...
    • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey 

      Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Systematic reviews experience major limitations in reporting absolute effects 

      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...