Browsing by Author "db49b2c0-3cf7-40d5-98df-989344db87e7"

Now showing items 1-4 of 4

    • Genetic variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 are associated ... 
      Morales, Sebastián; De Mayo, Tomas; Gulppi, Felipe Andrés; González Hormazábal, Patricio; Carrasco, Valentina; Reyes, José Miguel; Gómez, Fernando; Waugh, Enrique; Jara, Lilian (MDPI AG, 2018)
      © 2018 by the authors. Licensee MDPI, Basel, Switzerland. Breast cancer (BC) is one of the most frequent tumors affecting women worldwide. microRNAs (miRNAs) single-nucleotide polymorphisms (SNPs) likely contribute to BC ...
    • Germline variants in driver genes of breast cancer and their association with familial and early-onset ... 
      Fernández Moya, Alejandro; Morales, Sebastián; Arancibia, Trinidad; González Hormazábal, Patricio; Tapia, Julio; Godoy Herrera, Raúl; Reyes, José Miguel; Gómez, Fernando; Waugh, Enrique; Jara Sosa, Lilian (MDPI, 2020)
      The genetic variations responsible for tumorigenesis are called driver mutations. In breast cancer (BC), two studies have demonstrated that germline mutations in driver genes linked to sporadic tumors may also influence ...
    • RAD51 135G>C polymorphism and risk of familial breast cancer in a South American population 
      Jara, Lilian; Acevedo, Monica L.; Blanco, Rafael; Castro, Victor G.; Bravo, Teresa; Gómez, Fernando; Waugh, Enrique; Peralta, Octavio; Cabrera, Elsa; Reyes, José M.; Ampuero Llanos, Sandra; González Hormazábal, Patricio (2007)
      Several studies have reported that mutations in genes involved in maintenance of genome integrity may be responsible for increased cancer risk. Human RAD51, known to function in DNA repair, interacts with a number of ...
    • Variants in DNA double-strand break repair genes and risk of familial breast cancer in a South American population 
      Jara, Lilian; Dubois, Karen; Gaete, Daniel; De Mayo, Tomas; Ratkevicius, Nikalai; Bravo, Teresa; Margarit, Sonia; Blanco, Rafael; Gómez, Fernando; Waugh, Enrique; Peralta, Octavio; Reyes, Jose M.; Ibáñez, Gladys; González Hormazábal, Patricio (Springer New York, 2010)
      The double-strand break (DSB) DNA repair pathway has been implicated in breast cancer (BC). RAD51 and its paralogs XRCC3 and RAD51D play an important role in the repair of DSB through homologous recombination (HR). Some ...