Now showing items 1-2 of 2

    • ESR and spin trapping studies of two new potential antitrypanosomal drugs 

      Olea Azar, Claudio; Rigol Olsen, Carolina; Opazo, L.; Morello Casté, Antonio; Maya Arango, Juan; Repetto Scaramelli, Yolanda; Aguirre, G.; Cerecetto, Hugo; Di Maio, R.; González, M.; Porcal, Williams (SOCIEDAD CHILENA DE QUIMICA, 2003-12)
      The Electron Spin Resonance (ESR) spectra of radicals obtained from two new potential antitrypanosomal drugs by Trypanosoma cruzi reduction were analyzed. DMPO Spin Trapping was used to investigate the possible formation ...
    • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones 

      Aguirre, G.; Boiani, Lucía; Cerecetto, Hugo; Fernández, M.; González, M.; Denicola, Ana; Otero, L.; Gambino, Dinorah; Rigol Olsen, Carolina; Olea Azar, Claudio; Faúndez Cáceres, Mario Antonio (PERGAMON-ELSEVIER SCIENCE LTD, 2004-09-15)
      The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis, are described. The designed compounds combine ...