Browsing by Author "ef0e2893-1992-4f16-84db-3f3c8994a381"

Now showing items 1-12 of 12

    • Aberrant localization of ezrin correlates with salivary acini disorganization in Sjogren's Syndrome. 
      Pérez, Paola; Aguilera, Sergio; Olea, Nancy; Alliende, Cecilia; Molina, Claudio; Brito, Mónica; Barrera, María José; Leyton, Cecilia; Rowzee, Anne; González Burgos, María Julieta (2010)
      To analyse whether the alterations in the structure and organization of microvilli in salivary acinar cells from SS patients are linked to changes in the expression and/or cellular localization of ezrin. Salivary gland ...
    • Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro 
      Castro Masso, Isabel; Albornoz, Nicolás; Aguilera, Sergio; Barrera, María José; González, Sergio; Núñez, Matilde; Carvajal, Patricia; Jara, Daniela; Lagos, Carolina; Molina, Claudio; Urzúa Tobar, Ulises; Hermoso, Marcela; González Burgos, María Julieta (Oxford University Press, 2020)
      Objectives. Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate ...
    • Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and ... 
      Lagos, Carolina; Carvajal, Patricia; Castro, Isabel; Jara, Daniela; González, Sergio; Aguilera, Sergio; Barrera, María José; Quest, Andrew F. G.; Bahamondes, Verónica; Molina, Claudio; Urzúa, Ulises; Hermoso Ramello, Marcela; Leyton, Cecilia; González Burgos, María Julieta (Academic Press Inc., 2018)
      © 2018 Elsevier Inc.Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial ...
    • Changes in Rab3D expression and distribution in the acini of Sjögren's syndrome patients are associated ... 
      Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Ma (2011)
      Objective Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to ... 
      Ewert, Patricia; Aguilera, Sergio; Alliende, Cecilia; Kwon, Yoon Jeoung; Albornoz, Amelina; Molina, Claudio; Urzúa, Ulises; Quest, Andrew F. G.; Olea, Nancy; Pérez, Paola; Castro, Isabel; Barrera, María José; Romo, Rafael; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Mar (2010)
      Objective. Disorganization of acinar cell apical microvilli and the presence of stromal collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is impaired in patients with Sjögren's ...
    • Dual innervation of the brachialis muscle in the Chilean population Doble inervación del músculo braquial ... 
      Molina, Claudio; Uribe, Cristián; Heras, Álvaro; Astorga, Cristián; Lemus, Jorge; Rodríguez, Alberto (2011)
      The dual innervation of the brachialis muscle by the musculocutaneos nerve and branches from the radial nerve has been described by some anatomical texts and several scientific papers; however, there is no consensus about ...
    • Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded ... 
      Barrera, María José; Aguilera, Sergio; Castro, Isabel; González, Sergio; Carvajal, Patricia; Molina, Claudio; Hermoso, Marcela A.; González, María Julieta (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases. However, some studies have demonstrated the ...
    • Gene expression and chromosomal location for susceptibility to Sjögren's syndrome 
      Pérez, Paola; Anaya, Juan Manuel; Aguilera, Sergio; Urzúa Tobar, Ulises; Munroe, David; Molina, Claudio; Hermoso Ramello, Marcela; Cherry, James Michael; Alliende, Cecilia; Olea, Nancy; Ruiz-Narváez, Edward; González Burgos, María Julieta (2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • HSA-MIR-513C-3P overexpression decreases XBP-1S correlating with increased inflammation and autoantibodies ... 
      Carvajal, Patricia; Aguilera, Sergio; Heathcote, Bernard; Castro Masso, Isabel; Jara, Daniela; Barrera, María José; Maracajá Coutinho, Vinicius; González, S.; Aliaga, Vanina; Molina, Claudio; González Burgos, María Julieta (BMJ, 2020)
    • Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary ... 
      Kwon, Yoon Jeoung; Pérez, Paola; Aguilera, Sergio; Molina, Claudio; Leyton Campos, Lisette; Alliende, Cecilia; Leyton, Cecilia; Brito, Mónica; Romo, Rafael; González Burgos, María Julieta (2006)
      Objective. To investigate remodeling of the basal lamina of labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) by analyzing the expression of specific components that participate in its assembly and ...
    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome 
      Sung Hsieh, Hsiao; Castro, I.; González, S.; Aguilera, S.; Smorodinsky, N. I.; Quest, Andrew F. G.; Bahamondes Lorca, Verónica; Alliende, Cecilia; Cortés, J.; Molina, Claudio; Urzúa Tobar, Ulises; Barrera, María José; Hermoso Ramello, Marcela; Herrera Cisterna, Luisa; Leyton Martínez, Cecilia; González Burgos, María Julieta (Wiley-Blackwell, 2015)
      OBJECTIVES: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sj€ogren’s syndrome patients (SS patients), as well as their in vitro expression induced by ...
    • Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from ... 
      Cortés, Juan; Hidalgo, Jorge; Aguilera, Sergio; Castro, Isabel; Brito, Mónica; Urra, Hery; Pérez, Paola; Barrera, María José; Carvajal, Patricia; Urzúa, Ulises; González, Sergio; Molina, Claudio; Bahamondes, Verónica; Hermoso, Marcela; González, María Julieta (Academic Press, 2019)
      Sjögren's syndrome (SS) is an autoimmune exocrinopathy associated with severe secretory alterations by disruption of the glandular architecture integrity, which is fundamental for a correct function and localization of the ...