Now showing items 1-9 of 9

    • Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis 

      Brignardello Petersen, Romina; Bonner, Ashley; Alexander, Paul; Siemieniuk, Reed; Furukawa, Toshi; Rochwerg, Bram; Hazlewood, Glen; Alhazzani, Waleed; Mustafa, Reem; Murad, M. Hassan; Puhan, Milo; Sch€unemann, Holger; Guyatt, Gordon H. (Elsevier, 2018)
      This article describes conceptual advances of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group guidance to evaluate the certainty of evidence (confidence in evidence, quality of ...
    • Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane review users: study protocol for a randomized controlled trial 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per Olav; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Guyatt, Gordon H.; Schuenemann, Holger (BIOMED CENTRAL, 2015)
      Background: Systematic reviews represent one of the most important tools for knowledge translation but users often struggle with understanding and interpreting their results. GRADE Summary-of-Findings tables have been ...
    • Decision-Making about healthcare related tests and diagnostic strategies:user testing of GRADE evidence tables 

      Mustafa, Reem; Wiercioch, Wojtek; Santesso, Nancy; Cheung, Adrienne; Prediger, Bárbara; Baldeh, Tejan; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Bossuyt, Patrick; Garg, A.; Lelgemann, Monika; Bühler, Diedrich; Brozek, Jan; Schünemann, Holger (PLOS One, 2015)
      Objective:To develop guidance on what information to include and how to present it in tables summarizing the evidence from systematic reviews of test accuracy following the Grading of Recommendations Assessment, Development ...
    • Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE recommendations 

      Neumann, Ignacio; Alonso Coello, Pablo; Vandvik, Per; Agoritsas, Thomas; Mas, Gemma; Akl, Elie; Brignardello Petersen, Romina; Emparanza, José; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Rojas, Luis; Stirnemann, Jérôme; Irani, Jihad; Hlais, Sani; Mustafa, Reem; Bdair, Fadi; Aly, Abdelrahman; Kristiansen, Annette; Izcovich, Ariel; Ramírez Morera, Anggie; Brozek, Jan; Guyatt, Gordon H.; Schünemann, Holger (Elsevier, 2018-07)
      Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. However, some argue ...
    • Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Garner, Paul; Guyatt, Gordon H.; Sch€unemann, Holger (Elsevier, 2016)
      Objectives: The current format of summary of findings (SoFs) tables for presenting effect estimates and associated quality of evidence improve understanding and assist users finding key information in systematic reviews. ...
    • Improving GRADE evidence tables part 2: a systematic survey of explanatory notes shows more guidance is needed 

      Langendam, Miranda; Carrasco Labra, Alonso; Santesso, Nancy; Mustafa, Reem; Brignardello Petersen, Romina; Ventresca, Matthew; Heus, Pauline; Lasserson, Toby; Moustgaard, Rasmus; Brozek, Jan; Schunemann, Holger (Elsevier, 2016)
      Objectives: The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group has developed GRADE evidence profiles (EP) and summary of findings (SoF) tables to present evidence summaries in ...
    • Improving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments 

      Santesso, Nancy; Carrasco Labra, Alonso; Langendam, Miranda; Brignardello Petersen, Romina; Mustafa, Reem; Heus, Pauline; Lasserson, Toby; Opiyo, Newton; Kunnamo, Ilkka; Sinclair, David; Garner, Paul; Treweek, Shaun; Tovey, David; Akl, Elie; Tugwell, Peter; Brozek, Jan; Guyatt, Gordon H.; Schunemann, Holger (Elsevier, 2016)
      Background: The Grading of Recommendations Assessment, Development and Evaluation (GRADE) is widely used and reliable and accurate for assessing the certainty in the body of health evidence. The GRADE working group has ...
    • Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey 

      Kahale, Lara; Diab, Batoul; Brignardello Petersen, Romina; Agarwal, Arnav; Mustafa, Reem; Kwong, Joey; Neumann, Ignacio; Li, Ling; Cruz Lopes, Luciane; Briel, Matthias; Busse, Jason; Lorio, Alfonso; Vandvik, Per Olav; Alexander, Paul; Guyatt, Gordon H.; Akl, Elie (Elsevier, 2018-03-02)
      Objectives: To describe how systematic review authors report and address categories of participants with potential missing outcome data of trial participants. Study Design and Setting: Methodological survey of systematic ...
    • Systematic reviews experience major limitations in reporting absolute effects 

      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...