Now showing items 1-20 of 25

    • Pino Pinto, Juan Pablo; Oyarzún Ampuero, Felipe; Orellana, Sandra L.; Flores, Mario E.; Nishide, Hiroyuki; Moreno Villoslada, Ignacio (Elsevier, 2017)
      Aerogels made of chitosan and chondroitin sulfate, and containing 5,10,15,20-tetrakis-(4- sulfonatophenyl)-porphyrin have been synthesized. The aerogels presented a microstructure made of microfibers and microsheets, ...
    • Angélica Gómez, María; Marcela Bonilla, Jennifer; Alejandra Coronel, María; Martínez, Jonathan; Moran Trujillo, Luis; Orellana, Sandra L.; Vidal, Alejandra; Giacaman, Annesi; Morales, Carlos; Torres Gallegos, Cesar; Concha, Miguel; Oyarzún Ampuero, Felipe; Godoy, Patricio; Lisoni, Judit G.; Henríquez Baez, Carla; Bustos, Carlos; Moreno Villoslada, Ignacio (Walter de Gruyter GMBH, 2018-04)
      The antibacterial activity against Staphylococcus aureus of aerogels fabricated from colloidal suspensions of chitosan/chondroitin sulfate nanocomplexes is analyzed. Upon freeze-drying the colloidal suspensions, the aerogels ...
    • Vidal, Alejandra; Giacamán, Annesi; Orellana, Sandra S.; Jofré, Sandra; Moreno Villoslada, Ignacio; Oyarzún Ampuero, Felipe; Concha, Miguel (H M P Communications, 2020)
      Introduction. Diabetic foot ulcers may lead to nontraumatic amputations of the foot, leading to a decrease in patient quality of life. Transmetatarsal amputations (TMAs) represent an effective surgical procedure in cases ...
    • Orellana, Sandra L.; Torres Gallegos, César; Araya Hermosilla, Rodrigo; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (John Wiley, 2015)
      The association efficiency of oxytetracycline (OTC) to pharmaceutical available, ionic oil-in-water nanoemulsions is studied. Theoretical mathematical developments allowed us to differentiate by diafiltration (DF) between ...
    • García, Francisca; Lobos, Pedro; Ponce, Alejandra; Cataldo, Karla; Meza, Daniela; Farías, Patricio; Estay, Carolina; Oyarzún Ampuero, Felipe; Herrera Molina, Rodrigo; Paula Lima, Andrea; Ardiles, Álvaro O.; Hidalgo Tapia, Cecilia; Adasme, Tatiana; Muñoz, Pablo (MDPI, 2020)
      Astaxanthin (ASX) is a carotenoid pigment with strong antioxidant properties. We have reported previously that ASX protects neurons from the noxious effects of amyloid-beta peptide oligomers, which promote excessive ...
    • Orellana, Sandra L.; Giacaman, Annesi; Vidal, Alejandra; Morales, Carlos; Oyarzún Ampuero, Felipe; Lisoni, Judit G.; Henríquez Baez, Carla; Moran Trujillo, Luis; Concha Nordemann, Miguel; Moreno Villoslada, Ignacio (Walter de Gruyter GMBH, 2018-04)
      The formation of ultralight, highly porous solid materials (porosity higher than 99 %) containing equivalent molar amounts of chitosan (CS) and chondroitin sulfate (ChS) is presented. First, we show protocols to produce ...
    • Encina, Cristian; Vergara Hinostroza, Cristina; Giménez, Begoña; Oyarzún Ampuero, Felipe; Robert Canales, Paz (Elsevier, 2016)
      Polyunsaturated fatty acids, especially long-chain polyunsaturated omega-3 fatty acids (LCco3-PUFA), are essential in human nutrition because they play an important role in humans and prevent several diseases. Fish oil is ...
    • Silva, Wladimir; Torres Gatica, María Fernanda; Oyarzún Ampuero, Felipe; Silva Weiss, Andrea; Robert Canales, Paz; Cofrades, Susana; Giménez, Begoña (Elsevier, 2018)
      The development of fat replacers to obtain healthier/functional foods is a constant challenge. With this aim, double emulsions (DE) with a blend of olive, linseed and fish oils as oil phase were developed. To prevent the ...
    • Inostroza Riquelme, Mariela; Vivanco, Andrea; Lara, Pablo; Guerrero Rivera, Simón; Salas Huenuleo, Edison; Chamorro, Alejandro; Leyton Campos, Lisette; Bolaños, Karen; Araya Fuentes, Eyleen; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Oyarzún Ampuero, Felipe (MDPI, 2018-05)
      Here we report the incorporation of gold nanostructures (nanospheres or nanorods, functionalized with carboxylate-end PEG) and curcumin oil-in-water (O/W) nanoemulsions (CurNem) into alginate microgels using the dripping ...
    • Flores, Mario E.; Garcés Jerez, Pablo; Fernández, Daniel; Aros Pérez, Gustavo; González Cabrera, Diego; Álvarez, Eduardo; Cañas, Ignacio; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Wiley, 2016)
      The formation of redox-active, totally organic nanoparticles in water is achieved following a strategy similar to that used to form metal nanoparticles. It is based on two fundamental concepts: i) complexation through ...
    • Hassan, Natalia; Oyarzún Ampuero, Felipe; Muñoz Lara, Pablo; Guerrero, Simón; Cabuil, Valérie; Abou-Hassan, Ali; Kogan Bocian, Marcelo (Bentham Science Publishers B.V., 2014)
      In this article we review the flow chemistry methodologies for the controlled synthesis of different kind of nano and microparticles for biomedical applications. Injection mechanism has emerged as new alternative for the ...
    • Guerrero, Ariel R.; Oyarzún Ampuero, Felipe; Hassan, Natalia; Corvalán, Alejandro; Quest, Andrew F. G.; Kogan Bocian, Marcelo (Bentham Science, 2016)
      In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths ...
    • Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • Morales, Javier; Valdés, Karina; Morales, Javier; Oyarzún Ampuero, Felipe (Future Medicine Ltd., 2015)
      Retinoids are lipophilic compounds that are highly used in cosmetics/therapeutics for skin disorders. Conventional formulations are limited by poor water solubility, high chemical/photochemical instability and the irritation ...
    • Barraza, Paulo; Gómez, David M.; Oyarzún Ampuero, Felipe; Dartnell Roy, Pablo (Elsevier, 2014)
      Adults use different processing strategies to work with fractions. Depending on task requirements, theymay analyze the fraction components separately (componential processing strategy, CPS) or consider thefraction as a ...
    • Jara, Claudia; Oyarzún Ampuero, Felipe; Carrión, Flavio; González Echeverría, Esteban; Cappelli, Claudio; Caviedes Fernández, Pablo (BMC, 2020)
      Background: In type I diabetes mellitus (T1DM) pancreatic beta cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet ...
    • Oyarzún Ampuero, Felipe; Vidal, Alejandra; Concha, Miguel; Morales Montecinos, Javier; Orellana, Sandra; Moreno Villoslada, Ignacio (Bentham, 2015)
      The treatment of skin wounds represents an important research area due to the important physiological and aesthetic role of this tissue. During the last years, nanoparticles have emerged as important platforms to treat ...
    • Morales Montecinos, Javier; Sepúlveda Rivas, Sabrina; Oyarzún Ampuero, Felipe; Lavandero González, Sergio; Kogan Bocian, Marcelo (Bentham, 2015)
      Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of ...
    • Oyarzún Ampuero, Felipe; Guerrero Hernández, Ariel; Hassan López, Natalia; Morales Valenzuela, Javier; Bollo Dragnic, Soledad; Corvalán Rodríguez, Alejandro; Quest, Andrew F. G.; Kogan Bocian, Marcelo (Bentham, 2015)
      Organic and inorganic nanoparticles show great potential for cancer diagnosis and treatment. Because gastric cancer (GC) represents the second most deadly type of neoplasia worldwide, continued research efforts by scientists ...