Now showing items 21-40 of 40

    • Langendam, Miranda; Carrasco Labra, Alonso; Santesso, Nancy; Mustafa, Reem; Brignardello Petersen, Romina; Ventresca, Matthew; Heus, Pauline; Lasserson, Toby; Moustgaard, Rasmus; Brozek, Jan; Schunemann, Holger (Elsevier, 2016)
      Objectives: The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group has developed GRADE evidence profiles (EP) and summary of findings (SoF) tables to present evidence summaries in ...
    • Santesso, Nancy; Carrasco Labra, Alonso; Langendam, Miranda; Brignardello Petersen, Romina; Mustafa, Reem; Heus, Pauline; Lasserson, Toby; Opiyo, Newton; Kunnamo, Ilkka; Sinclair, David; Garner, Paul; Treweek, Shaun; Tovey, David; Akl, Elie; Tugwell, Peter; Brozek, Jan; Guyatt, Gordon H.; Schunemann, Holger (Elsevier, 2016)
      Background: The Grading of Recommendations Assessment, Development and Evaluation (GRADE) is widely used and reliable and accurate for assessing the certainty in the body of health evidence. The GRADE working group has ...
    • Brignardello Petersen, Romina; Guyatt, Gordon H.; Buchbinder, Rachelle; Poolman, Rudolf W.; Schandelmaier, Stefan; Chang, Yaping; Sadeghirad, Behnam; Evaniew, Nathan; Vandvik, Per O. (BMJ Publishing Group, 2017)
      Objective: To determine the effects and complications of arthroscopic surgery compared with conservative management strategies in patients with degenerative knee disease. Design: Systematic review. Main outcome ...
    • Vandvik, Per; Brignardello Petersen, Romina; Guyatt, Gordon H. (BIOMED CENTRAL, 2016)
      In a recent research article in BMC Medicine, Crequit and colleagues demonstrate how published systematic reviews in lung cancer provide a fragmented, out-of-date picture of the evidence for all treatments. The results and ...
    • Rojas Alcayaga, Gonzalo; Brignardello Petersen, Romina; Espinoza Santander, Iris; Franco Martínez, María Eugenia; Lobos Jaimes-Freyre, Nelson; Ortega Pinto, Ana (Argentine Division of the International Association for Dental Research, 2010-08)
      El objetivo de este estudio fue describir las principales características clínicas y la frecuencia relativa de cada tipo de neoplasia maligna bucal recibidas en el Instituto de Referencia en Patología Oral (IREPO) de la ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Yanine Montaner, Nicolás; Ulloa Marín, Carolina; Araya Cabello, Ignacio; Pintor, Fernanda; Villanueva Maffei, Julio; Cornejo Ovalle, Marco (American Dental Association, 2013)
      Background. The relationship between industry funding and study results has been explored widely in medicine but not in dentistry. The authors aimed to assess the relationship between conflicts of interest (COIs) and ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (AMER DENTAL ASSOC, 2015)
      Background and Overview. Dental practitioners spend most of their time administering treatments. To ensure that their clinical decisions are informed by the best available evidence, dental practitioners need to be skilled ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding harm are common in dental practice. Observational, nonrandomized studies (that is, cohort studies and casecontrol studies) are the designs used by investigators to answer most ...
    • Abrahamyan, Lusine; Pechlivanoglou, Petros; Krahn, Murray; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Background and Overview. In everyday practice, dentists face clinical decisions for which they need to consider both treatment consequences (that is, benefits and harms) and costs. Economic analysis is a study design in ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding diagnosis are common in dental practice. Studies in which investigators apply a diagnostic test and a reference standard to all patients and compare their results represent the ...
    • Sale, Joanna E. M; Amin, Maryam; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Because of qualitative researchers' abilities to explore social problems and to understand the perspective of patients, qualitative research studies are useful to provide insight about patients' ...
    • Brignardello Petersen, Romina; Carrasco Labra, Raúl (American Dental Association, 2013-07)
      Background. It is common to find published studies in which the authors claim to have found significant results. However, many times these results are only statistically significant with no meaningful impact in clinical ...
    • Brignardello Petersen, Romina; Carrasco Labra, Raúl; Shah, Prakeshkumar; Azarpazhooh, Amir (American Dental Association, 2013)
      Background. It is common to find published studies in which the authors claim to have found significant results. However, many times these results are only statistically significant with no meaningful impact in clinical ...
    • Alibhai, Shabbir M. H.; Breunis, Henriette; Timilshina, Narhari; Brignardello Petersen, Romina; Tomlinson, George; Mohamedali, Hassanabbas; Gupta, Vikas; Minden, Mark D.; Li, Madeline; Buckstein, Rena; Brandwein, Joseph M. (Elsevier, 2015)
      Objectives: Intensive chemotherapy (IC) is the primary treatment of acute myeloid leukemia (AML) but is associated with significant toxicity, particularly in older adults. We characterized the impact of AML and its treatment ...
    • Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Kahale, Lara; Diab, Batoul; Brignardello Petersen, Romina; Agarwal, Arnav; Mustafa, Reem; Kwong, Joey; Neumann, Ignacio; Li, Ling; Cruz Lopes, Luciane; Briel, Matthias; Busse, Jason; Lorio, Alfonso; Vandvik, Per Olav; Alexander, Paul; Guyatt, Gordon H.; Akl, Elie (Elsevier, 2018-03-02)
      Objectives: To describe how systematic review authors report and address categories of participants with potential missing outcome data of trial participants. Study Design and Setting: Methodological survey of systematic ...
    • Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...
    • Agoritsas, Thomas; Merglen, Arnaud; Heen, Anja Fog; Kristiansen, Annette; Neumann, Ignacio; Brito, Juan P.; Brignardello Petersen, Romina; Alexander, Paul E.; Rind, David M.; Vandvik, Per O.; Guyatt, Gordon H. (BMJ Publishing Group, 2017)
      Introduction UpToDate is widely used by clinicians worldwide and includes more than 9400 recommendations that apply the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. GRADE guidance ...
    • Brignardello Petersen, Romina; Johnston, Bradley C.; Jadad, Alejandro; Tomlinson, George (Elsevier, 2018)
      Objectives: To evaluate how the rank probabilities obtained from network meta -analysis (NMA) change with the use of increasingly stringent criteria for the relative effect comparing two treatments which ranks one treatment ...