Now showing items 40221-40240 of 91507

    • Liberona Leppe, José; Caviedes Fernández, Pablo; Tascón, S.; Hidalgo Tapia, Jorge; Giglio, J. R.; Sampaio, S. V.; Caviedes, R.; Jaimovich Pérez, Enrique (Chapman Hall, 1997)
      An immortal, cloned cell Line (RCMH), obtained from human skeletal muscle was established in our laboratory and shown to express muscle specific proteins. We measured ligand binding to ion channels, ion currents using whole ...
    • Amweg, A. N.; Paredes, A.; Salvetti, N. R.; Lara Peñaloza, Hernán; Ortega, H. H. (Elsevier, 2011)
      Melanocortin receptors (MCRs) are involved in physiological responses to ACTH, as well as to -, - and -melanocytestimulating hormone ( -, - and -MSH). Their expression has previously been analyzed in various bovine ...
    • García Díaz, Diego; Pizarro, Carolina; Camacho Guillen, Patricia; Codner Dujovne, Ethel; Soto, Nestor; Pérez Bravo, Francisco (Sbem-Soc Brasil Endocrinología & Metabología, 2018)
      Objective: The aim of this research was to analyze the expression profile of miR-155, miR-146a, and miR-326 in peripheral blood mononuclear cells (PBMC) of 47 patients with type 1 diabetes mellitus (T1D) and 39 control ...
    • Estrella, Santiago; García Díaz, Diego; Codner Dujovne, Ethel; Camacho Guillen, Patricia; Pérez Bravo, Francisco (2016)
      Background and objective: Type 1 diabetes (T1D) is an autoimmune disease of complex aetiology. Several microRNAs (miR) have been linked to the pathogenesis of autoimmune diseases. To analyze the possible association ...
    • Estrella, Santiago; García Díaz, Diego; Codner Dujovne, Ethel; Camacho-Guillén, Patricia; Pérez Bravo, Francisco (Ediciones Doyma, S.L., 2016)
      © 2016 Elsevier España, S.L.U. Background and objective Type 1 diabetes (T1D) is an autoimmune disease of complex aetiology. Several microRNAs (miR) have been linked to the pathogenesis of autoimmune diseases. To analyze ...
    • Avellaira, C.; Villavicencio, A.; Bacallao, Ketty; Gabler Neale, Fernando; Wells, P.; Romero Osses, Carmen; Vega Blanco, María Margarita (Oxford University Press, 2006)
      Background: The hormonal alterations observed in women with polycystic ovary syndrome (PCOS) may promote implantation failure as well as disruption of their endometrial homeostasis. To evaluate cell survival of mid-secretory ...
    • Sánchez, Catherine; Mendoza, Patricia; Contreras, Héctor R.; Vergara, Jorge; McCubrey, James A.; Huidobro, Christian; Castellón, Enrique A. (2009)
      BACKGROUND. Multidrug resistance (MDR) proteins have been associated with the lack of chemotherapy response. Expression of these proteins has been described in the prostate, but there is no information about their role in ...
    • Cuevas, Ada M.; Lazo, Mariana; Zúñiga, Isabel; Carrasco, Fernando; Potter, Jim J.; Álvarez, Verónica; Berry, Marcos; Maluenda, Fernando; Ferrario, Mario; Clark, Jeanne M. (Mary Ann Liebert, 2017)
      BACKGROUND: The mechanism leading to the development of metabolic complications in obese individuals is not fully understood. Thus, the objective of this study was to examine differences in insulin resistance, inflammation, ...
    • Infante Fabres, Claudio; Díaz, Marcelo; Hernández, Alejandro; Constandil, Luis; Pelissier Serrano, Teresa (2007)
      Chronic pain is associated with N-methyl-D-aspartate (NMDA) receptor activation and downstream production of nitric oxide, which has a pivotal role in multisynaptic local circuit nociceptive processing in the spinal cord. ...
    • Mione, Marina; Lele, Zsolt; Kwong, Camilla T.; Concha, Miguel L.; Clarke, Jonathan D. (WILEY-LISS, DIV JOHN WILEY & SONS, 2006-04-20)
      The molecular organization of the zebrafish brain and its relation to neuroanatomical divisions are still largely unknown. In this study we have analyzed the expression of a small transcript encoding for the IQ containing ...
    • Vernal Astudillo, Rolando; Velásquez, Edgar; Gamonal Aravena, Jorge Antonio; García Sanz, José A.; Silva, Augusto; Sanz, Mariano (PERGAMON-ELSEVIER SCIENCE LTD, 2008-10)
      Objective: This study reports the expression of proinflammatory cytokines in temporomandibular joint (TMJ) of patients affected with temporomandibular osteoarthritis (OA). Design: In twelve OA of the TMJ (OA–TMJ) affected ...
    • Tapia Castillo, Alejandra; Carvajal, Cristian; Campino, Carmen; Hill, Caroline; Allende, Fidel; Vecchiola, Andrea; Carrasco, Carmen; Bancalari, Rodrigo; Valdivia, Carolina; Lagos, Carlos; Martínez Aguayo, Alejandro; García, Hernán; Aglony, Marlene; Baudrand, René; Kalergis, Alexis; Michea Acevedo, Luis; Riedel, Claudia; Fardella, Carlos (Oxford University Press, 2015)
      BACKGROUND Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect the expression of oxidative stress markers, such as ...
    • Stanic, Karen; Quiroz, Alonso; Lemus, Carmen G.; Wichmann, Ignacio A.; Corvalan, Alejandro H.; Owen, Gareth I.; Opazo, Juan C.; Concha Nordemann, Miguel; Amigo, Julio D. (Frontiers media SA, 2018)
      The Reprimo (RPRM) family is composed of highly conserved single-exon genes. The expression pattern of this gene family has been recently described during zebrafish (Danio rerio) embryogenesis, and primarily locates in the ...
    • Caballero, Valeria C.; Toledo, Viviana; Maturana, Cristian; Fisher, Carolyn R.; Payne, Shelley M.; Salazar, Juan Carlos (2012)
      Background: Glutamyl queuosine-tRNAAsp synthetase (GluQ-RS) is a paralog of the catalytic domain of glutamyl-tRNA synthetase and catalyzes the formation of glutamyl-queuosine on the wobble position of tRNAAsp. Here we ...
    • Ocaranza, Paula; Morales, Fernanda; Román, Rossana; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (2012)
      Background/aim: Possible etiologies of idiopathic short stature (ISS) include a range of conditions, some of which may be caused by defects in the modulation of the growth hormone (GH)-signaling pathway. The Janus kinase/signal ...
    • Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)
      Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
    • Lodato, Patricia; Alcaíno Gorman, Jennifer; Barahona‑Crisóstomo, Salvador; Niklitschek, Mauricio; Carmona, M.; Wozniak, A.; Baeza Paredes, Mauricio; Jiménez, A.; Cifuentes Guzmán, Víctor (2007)
      In the yeast Xanthophyllomyces dendrorhous the genes idi, crtE, crtYB, crtI and ast are involved in the biosynthesis of astaxanthin from isopentenyl pyrophosphate. The carotenoid production and the kinetics of mRNA expression ...
    • Araya López, Héctor; Sepulveda, Hugo; Lizama, Carlos O.; Vega Villa, Oscar; Jerez, Sofia; Briceño, Pedro F.; Thaler, Roman; Riester, Scott M.; Antonelli Anativia, Marcelo; Salazar Onfray, Flavio; Rodríguez Vives, Juan Pablo; Moreno, Ricardo D.; Montecino, Martín; Charbonneau, Martine; Dubois, Claire; Galindo Díaz, Mario; Stein, Gary; van Wijnen, Andre (Wiley-Liss Inc., 2018)
      Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
    • Salas Cortés, Laura; Jaubert, Francis; Bono Merino, María Rosa; Fellous, Marc; Rosemblatt Silber, Mario César (2001)
      Sex determination in mammals is controlled by the SRY gene located on the Y chromosome. It encodes a protein containing a DNA-binding and DNA-bending domain. In spite of recent advances in the identification of the mechanisms ...
    • Dissen, Gregory A.; Garcia-Rudaz, Cecilia; Tapia, Veronica; Parada, Luis F.; Hsu, Sheau Yu Teddy; Ojeda, Sergio R. (2006)
      The insulin receptor-related receptor (IRR) is a member of the insulin receptor family that, on its own, recognizes neither insulin nor any of the identified insulin-related peptides. In both the nervous system and peripheral ...