Browsing by Subject "Gabapentin"

Now showing items 1-5 of 5

    • Antinociceptive interaction of gabapentin with minocycline in murine diabetic neuropathy 
      Miranda, H. F.; Sierralta, F.; Jorquera, V.; Poblete, P.; Prieto, J. C.; Noriega, V. (Birkhauser Verlag AG, 2017)
      © 2017, Springer International Publishing. Objective: Diabetic neuropathy (DN) is the most common complication of diabetes and pain is one of the main symptoms of diabetic neuropathy, however, currently available drugs are ...
    • Gabapentin increases expression of δ subunit-containing GABA A receptors 
      Yu, Jieying; Wang, Dian Shi; Bonin, Robert P.; Penna Silva, Antonello; Alavian-Ghavanini, Ali; Zurek, Agnieszka A.; Rauw, Gail; Baker, Glen B.; Orser, Beverley A. (Elsevier, 2019)
      Background: Gabapentin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Its anticonvulsant, analgesic and anxiolytic properties suggest that it increases GABAergic inhibition; however, ...
    • Interleukin-1beta in synergism gabapentin with tramadol in murine model of diabetic neuropathy 
      Miranda, H. F.; Poblete, P.; Sierralta, F.; Noriega, V.; Prieto, J. C.; Zepeda, R. J. (Birkhauser Verlag AG, 2019)
      Neuropathic pain is a complication of cancer and diabetes mellitus and the most commonly used drugs in the treatment of the diabetic neuropathic pain have only limited efficacy. The aim of this study was to evaluate the ...
    • Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial ... 
      Miranda, Hugo; Sierralta, Fernando; Lux, Sebastian; Troncoso, Rocío; Ciudad, Natalia; Zepeda Iriarte, Ramiro; Zanetta, Pilar; Noriega, Viviana; Prieto, Juan Carlos (Elsevier, 2015)
      Background: Pain is one of the most common problems in clinical medicine. There is considerable evidence that pharmacologic approaches are the most widely used therapeutic options to ameliorate persistent or chronic pain. ...
    • Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain 
      Miranda, Hugo F.; Noriega, Viviana; Zanetta, Pilar; Prieto, Juan Carlos (Quintessence Publishing Co. Inc., 2013)
      © Quintessence. Aims: To evaluate the nature of the antinociceptive interaction of systemic administration of a combination of the anticonvulsant gabapentin with the antidepressant nortriptyline, by isobolographic analysis ...