Browsing by Author "0bfbdcf1-da30-43fe-bea6-13ac50c82940"

Now showing items 1-6 of 6

    • Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically ... 
      Román Albasini, Luciano; Díaz Véliz, Gabriela; Olave, Felipe Antonio; Aguayo, Felipe Ignacio; García Rojo, Gonzalo; Corrales, Wladimir Antonio; Silva, Juan Pablo; Ávalos, Ana María; Rojas, Paulina S.; Aliaga, Esteban; Fiedler, Jenny Lucy (Elsevier, 2020)
      Several lines of evidence suggest that antidepressant drugs may act by modulating neuroplasticity pathways in key brain areas like the hippocampus. We have reported that chronic treatment with fasudil, a Rho-associated protein ...
    • Chronic stress triggers expression of immediate early genes and differentially affects the expression of ... 
      Pacheco Zapata, Aníbal; Aguayo, Felipe I.; Aliaga, Esteban; Muñoz, Mauricio; García Rojo, Gonzalo; Olave, Felipe A.; Parra Fiedler, Nicolás; García Pérez, Alexandra; Tejos Bravo, Macarena; Rojas, Paulina S.; Parra, Claudio S.; Fiedler Temer, Jenny (Frontiers media SA, 2017)
      Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared ...
    • Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study 
      Aguayo, Felipe Ignacio; Tejos Bravo, Macarena; Díaz Véliz, Gabriela; Pacheco Zapata, Aníbal; García Rojo, Gonzalo; Corrales, Wladimir; Olave, Felipe Antonio; Aliaga, Esteban; Ulloa, José L.; Avalos, Ana M.; Román Albasini, Luciano; Rojas, Paulina S.; Fiedler Temer, Jenny (Frontiers Media S.A., 2018)
      © 2018 Aguayo, Tejos-Bravo, Díaz-Véliz, Pacheco, García-Rojo, Corrales, Olave, Aliaga, Ulloa, Avalos, Román-Albasini, Rojas and Fiedler. Several studies have shown that a single exposure to stress may improve or impair ...
    • MicroRNA profiling and bioinformatics target analysis in dorsal hippocampus of chronically stressed rats: ... 
      Muñoz Llanos, Mauricio; García Pérez, María A.; Xu, Xiaojiang; Tejos Bravo, Macarena; Vidal, Elena A.; Moyano, Tomás C.; Gutiérrez, Rodrigo A.; Aguayo, Felipe I.; Pacheco Zapata, Aníbal; García Rojo, Gonzalo; Aliaga, Esteban; Rojas, Paulina S.; Cidlowski, John A.; Fiedler Temer, Jenny (Frontiers Media, 2018)
      Studies conducted in rodents subjected to chronic stress and some observations in humans after psychosocial stress, have allowed to establish a link between stress and the susceptibility to many complex diseases, including ...
    • Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor ... 
      Peralta, Francisco; Fuentealba, Constanza; Fiedler Temer, Jenny; Aliaga, Esteban (Spandidos Publ. Ltd., 2016)
      Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by deficits in social communication and social interaction, and repetitive and stereotypical patterns of behavior. Previously, a ...
    • The ROCK inhibitor fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic ... 
      García Rojo, Gonzalo; Fresno, Cristóbal; Vilches Peñaloza, Natalia; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Aguayo Abarca, Felipe; Pacheco Zapata, Aníbal; Parra Fiedler, Nicolás; Parra, Claudio; Rojas Domínguez, Paulina; Tejos Bravo, Macarena; Aliaga, Esteban; Fiedler Temer, Jenny (Oxford University Press, 2017-04-01)
      Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...