Now showing items 21-40 of 82

    • Báez Cornejo, Daniela; Ramos Peroni, Gabriel; Corvalán Aguilar, Alejandro; Cordero Garayar, María Luisa; Bollo Dragnic, Soledad; Kogan Bocian, Marcelo (Elsevier, 2020)
      Artificial micromotors evolve to improve multitasking performance in different research areas, and different power sources are combined to give rise to hybrid micromotors. Such combinations can alter physical features and ...
    • Sierra Rosales, Paulina; Torres, Rodrigo; Sepulveda, Carlos; Kogan Bocian, Marcelo; Squella Serrano, Juan (Wiley, 2018)
      Gold nanoparticles (AuNPs) have unique properties, making them attractive for electronic and energy-conversion devices and as (electro)catalysts for electrochemical sensors. In addition to the size and shape of AuNPs, the ...
    • Álvarez Lueje, Alejandro; Zapata Urzúa, Claudio Andrés; Brain Isasi, S.; Pérez Ortiz, María Magdalena; Barros, L.; Pessoa Mahana, Hernán; Kogan Bocian, Marcelo (ELSEVIER SCIENCE BV, 2009-08-15)
      The present study addresses the electrochemical behavior and the analytical applications of six 2-nitrophenylbenzimidazole derivatives with activity against Trypanosoma cruzi. When studied in a wide range of pH, by ...
    • Inostroza Riquelme, Mariela; Vivanco, Andrea; Lara, Pablo; Guerrero Rivera, Simón; Salas Huenuleo, Edison; Chamorro, Alejandro; Leyton Campos, Lisette; Bolaños, Karen; Araya Fuentes, Eyleen; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Oyarzún Ampuero, Felipe (MDPI, 2018-05)
      Here we report the incorporation of gold nanostructures (nanospheres or nanorods, functionalized with carboxylate-end PEG) and curcumin oil-in-water (O/W) nanoemulsions (CurNem) into alginate microgels using the dripping ...
    • Adura, Carolina; Guzman, Fanny; Álvarez Lueje, Alejandro; Kogan Bocian, Marcelo (Sociedad Chilena de Quimica, 2015)
    • Morales Alvarez, Aurora (Universidad de Chile, 2008)
      La proteína beta amiloide (Aβ), involucrada en la enfermedad de Alzheimer, cambia su conformación en condiciones patológicas formando agregados tóxicos (AT) que tienen un efecto neurodegenerativo. La estructura molecular ...
    • Sierpe Bustamante, Rodrigo Alfredo (Universidad de Chile, 2016)
      Las nanopartículas metálicas (NPsM), específicamente, las nanopartículas de oro (NPsAu) y las nanopartículas de plata (NPsAg), exhiben excelentes propiedades físicas, químicas y biológicas, intrínsecas a su tamaño ...
    • Marambio Retamal, Héctor Pablo (Universidad de ChilePrograma Cybertesis, 2007)
      La nanotecnología, en la biomedicina, trabaja desarrollando herramientas, tanto de diagnóstico, como estrategias terapéuticas, menos invasivas y más eficientes que las actualmente en uso. Entre estas herramientas, se ...
    • Guerrero Hernández, Ariel Rodrigo (Universidad de Chile, 2008)
      Esta memoria de título se inscribe en el marco del proyecto del desarrollo de la estrategia terapéutica basada en conjugados entre péptidos y nanopartículas metálicas como herramientas de diagnóstico y tratamiento para la ...
    • Vetterlein, Claudia; Vásquez Salfate, Rodrigo; Bolaños, Karen; Acosta, Gerardo A.; Guzman, Fanny; Albericio, Fernando; Celis, Freddy; Campos, Marcelo; Kogan Bocian, Marcelo; Araya, Eyleen (Elsevier, 2018-06)
      We studied the photothermal release of carboxyfluorescein (CF) linked to the gold surface of gold nanorods (GNRs) by two Diels-Alder adducts of different lengths (n = 4 and n = 9). The functionalized GNRs were irradiated ...
    • Arimon, M.; Diez Pérez, I.; Kogan Bocian, Marcelo; Durany, N.; Giralt, Ernest; Sanz, F.; Fernández Busquets, X. (FEDERATION AMER SOC EXP BIOL., 2005-05)
      One of the hallmarks of Alzheimer's disease is the self-aggregation of the amyloid beta peptide (A beta) in extracellular amyloid fibrils. Among the different forms of A beta, the 42-residue fragment (A beta(1-42)) readily ...
    • Hassan, Natalia; Oyarzún Ampuero, Felipe; Muñoz Lara, Pablo; Guerrero, Simón; Cabuil, Valérie; Abou-Hassan, Ali; Kogan Bocian, Marcelo (Bentham Science Publishers B.V., 2014)
      In this article we review the flow chemistry methodologies for the controlled synthesis of different kind of nano and microparticles for biomedical applications. Injection mechanism has emerged as new alternative for the ...
    • Guerrero, Ariel R.; Oyarzún Ampuero, Felipe; Hassan, Natalia; Corvalán, Alejandro; Quest, Andrew F. G.; Kogan Bocian, Marcelo (Bentham Science, 2016)
      In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths ...
    • Lara, Pablo; Palma Florez, Sujey; Salas Huenuleo, Edison; Polakovicova, Iva; Guerrero, Simón; Lobos González, Lorena; Campos, América; Muñoz, Luis; Jorquera Cordero, Carla; Varas Godoy, Manuel; Cancino, Jorge; Arias, Eloísa; Villegas, Jaime; Cruz, Luis J.; Albericio, Fernando; Araya, Eyleen; Corvalán, Alejandro H.; Quest, Andrew F. G.; Kogan Bocian, Marcelo (BMC, 2020)
      Background Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at ...
    • Riveros, Ana; Dadlani, Komal; Salas, Edison; Caballero, Leonardo; Melo, Francisco; Kogan Bocian, Marcelo (American Scientific Publishers, 2013)
      There has been an increase in the research towards the use of nanoparticles as a promising tool for nanomedicine, from imagenology, drug and gene delivery, to phototherapy. Little is known regarding the interaction between ...
    • Araya, Eyleen; Olmedo, Ivonne; Bastus, Neus G.; Guerrero, Simón; Puntes, Víctor F.; Giralt, Ernest; Kogan Bocian, Marcelo (SPRINGER, 2008-11)
      Peptide-Gold nanoparticles selectively attached to beta-amyloid protein (A beta) amyloidogenic aggregates were irradiated with microwave. This treatment produces dramatic effects on the A beta aggregates, inhibiting both ...
    • Pérez Ortiz, Magdalena; Zapata Urzua, Claudio; Acosta, Gerardo A.; Álvarez Lueje, Alejandro; Albericio, Fernando; Kogan Bocian, Marcelo (Elsevier, 2017)
      In this work, the potential application of gold nanoparticles for GLP-1 analogues delivery was studied. For this purpose, the original sequence of the incretin GLP-1 was slightly modified in the C-terminal region by adding ...
    • Guerrero, Ariel R.; Hassan, Natalia; Escobar, Carlos A.; Albericio, Fernando; Kogan Bocian, Marcelo; Araya, Eyleen (Future Medicine Ltd., 2014)
      © 2014 Future Medicine Ltd. In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is ...
    • Bastus, Neus G.; Kogan Bocian, Marcelo; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Victor F. (2007)
      Nanoparticles can be made to respond resonantly to a time-varying electromagnetic field with advantageous results related to the transfer of energy from the exciting field to the nanoparticles. The surface of each particle ...
    • Sierpe, Rodrigo; Lang, Erika; Jara, Paul; Guerrero, Ariel; Chornik, Boris; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás (American Chemical Society, 2015)
      We report the synthesis of a 1:1 beta-cydodextrin-phenylethylamine (beta CD-PhEA) inclusion complex (IC) and the adhesion of gold nanoparticles (AuNPs) onto micro crystals of this complex, which forms a ternary system. The ...