Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions
Now showing items 1-20 of 4211
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Influencia de los pingüinos barbijo (Pygoscelis antarctica) sobre la comunidad procarionte y el gremio de microorganismos diazotróficos en suelos de Isla Decepción, Antártica
(Universidad de Chile, 2020)Los pingüinos transfieren (ej. mediante guano, huevos, etc) cantidades significantes de nutrientes y contaminantes desde el ecosistema marino al ecosistema terrestre. Las deposiciones de estas aves influencian fuertemente ... -
Identificación de macrófagos M1 y M2 en aorta de ratas espontáneamente hipertensas (SHR) mediante citometría de flujo
(Universidad de Chile, 2020)Antecedentes. Las enfermedades cardiovasculares son la principal causa de muerte en el mundo y en nuestro país. El principal factor de riesgo es la hipertensión arterial (HTA). En Chile, el 26,9% de la población es hipertensa. ... -
Estrategias de preparación de muestra para la determinación espectrofluorimétrica de quinolonas y tetraciclinas de uso veterinario
(Universidad de Chile, 2020)En primera instancia, se estudió la conducta espectral de cada uno de los analitos pertenecientes a las familias involucrados en la investigación. Para seleccionar la longitud de excitación de los analitos en estudio se ... -
Estudio exploratorio de la destinación intracelular de las hemocianinas de moluscos a compartimentos endosomales en células presentadoras de antígeno murinas
(Universidad de Chile, 2020)Las hemocianinas de moluscos son ampliamente conocidas por sus efectos inmunomoduladores y, además, por ser utilizadas como carrier/adyuvante de antígenos tumorales. Sus efectos sobre el sistema inmune han sido atribuidos ... -
Reactivity descriptors for Cu bis-phenanthroline catalysts for the hydrogen peroxide reduction reaction
(Pergamon-Elsevier Science, 2020)Following previous studies where the metal-centered redox potentials of MN4 complexes are proposed as a reactivity descriptor for different electrochemical reactions, in the present work we expand this idea to a series of ... -
Evaluación cuantitativa y cualitativa del compromiso gerencial para la implementación de las buenas prácticas de fabricación en establecimientos de alimentos en la Región Metropolitana de Santiago
(Universidad de Chile, 2014)La alimentación es una de las necesidades básicas de los seres humanos, lo que ha generado una búsqueda incesante de nuevas fuentes de alimentos y/o preparaciones, los que a su vez deben cumplir con una serie de características, ... -
Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands
(MDPI, 2020)A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a-o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)- ... -
Metabolic specialization and codon preference of lignocellulolytic genes in the white rot basidiomycete ceriporiopsis subvermispora
(MDPI, 2020)Ceriporiopsis subvermispora is a white-rot fungus with a high specificity towards lignin mineralization when colonizing dead wood or lignocellulosic compounds. Its lignocellulose degrading system is formed by cellulose ... -
Airborne Aerosols and Human Health: Leapfrogging from Mass Concentration to Oxidative Potential
(MDPI, 2020)The mass concentration of atmospheric particulate matter (PM) has been systematically used in epidemiological studies as an indicator of exposure to air pollutants, connecting PM concentrations with a wide variety of human ... -
Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines
(Royal Society of Chemistry, 2020)Continuous flow chemistry was used for the synthesis of a series of delocalized lipophilic triphenylphosphonium cations (DLCs) linked by means of an ester functional group to several hydroxylated benzoic acid derivatives ... -
Vaccines against components of the renin-angiotensin system
(Springer, 2020)Even though effective drugs for treating hypertension are available, a great percentage of patients have inadequate control of their blood pressure. Unwanted side effects and inappropriate oral drug adherence are important ... -
Health-promoting activities of edible seaweed extracts from Chilean coasts: assessment of antioxidant, anti-diabetic, anti-inflammatory and antimicrobial potential
(Sociedad Chilena de Nutrición, 2020)The aim of this study was to evaluate the antioxidant, antidiabetic, anti-inflammatory and antimicrobial activities of three edible seaweed extracts from Chilean coasts: Pyropia orbicularis, Ulva spp, and Durvillaea ... -
Integration of Community pharmacy and pharmacists in primary health care policies in Argentina
(Centro Investigaciones & Publicaciones Farmacéuticas, España, 2020)Argentina is a federal republic with approximately 44 million people, divided into 23 provinces and an autonomous city, Buenos Aires. The health system is segmented into public, social security and private subsystems. The ... -
Determinación de los conocimientos, actitudes y prácticas en inocuidad alimentaria en estudiantes de profesiones vinculadas a la alimentación
(Universidad de Chile, 2018)Los alimentos insalubres generan un círculo vicioso de enfermedades y malnutrición, que esta afectando a una parte de la población especialmente a niños pequeños, ancianos y enfermos. Los jóvenes adultos tienen un conocimiento ... -
Rotating-disk sorptive extraction for the determination of sex hormones and triclosan in urine by gas chromatography-mass spectrometry: Clean-up integrated steps and improved derivatization
(Elsevier, 2020)Different clean-up stages were coupled to rotating-disk sorptive extraction (RDSE) of testosterone, progesterone, 17 beta-estradiol and triclosan in urine samples prior to derivatization and detection by gas chromatography-mass ... -
The Utility of Optical Satellite Winter Snow Depths for Initializing a Glacio-Hydrological Model of a High-Elevation, Andean Catchment
(American Geophysical Union, 2020)Information about end-of-winter spatial distribution of snow depth is important for seasonal forecasts of spring/summer streamflow in high-mountain regions. Nevertheless, such information typically relies upon extrapolation ... -
Delivery of ionizable hydrophilic drugs based on pharmaceutical formulation of ion pairs and ionic liquids
(Elsevier, 2020)New therapeutics such as antisense oligonucleotides, small interfering RNA and peptide-drug conjugates are taking great relevance in the pharmaceutical industry due to their specificity of action and their improved safety ... -
Effect of processing on texture and microstructure of the seaweed Durvillaea antarctica
(Springer, 2020)The algaeDurvillaea antarctica(cochayuyo) is the most popular edible seaweed in Chile and shows extensive variability at the marketplace. The objective of this study was to characterize the sample ofD. antarcticaand modify ...
