Browsing by Author "1880b37f-7022-4e59-a0c7-d63a2e973b58"

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    • Chaski, a novel drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional ... 
      Delgado, María Graciela; Oliva, Carlos; López, Estefanía; Ibacache, Andrés; Galaz, Alex; Delgado, Ricardo; Barros, L. Felipe; Sierralta, Jimena (Nature Publishing Group, 2018)
      The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the ...
    • Drosophila Atlastin in motor neurons is required for locomotion and presynaptic function 
      De Gregorio, Cristián; Delgado Arriagada, Ricardo; Ibacache, Andrés; Sierralta Jara, Jimena; Couve Correa, Andrés (Company of Biologists Ltd., 2017)
      Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...