Browsing by Author "201-0020935"
Now showing items 1-16 of 16
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(2010)Los avances en farmacología clínica muestran que la edad afecta considerablemente la farmacocinética de los medicamentos, por lo tanto, sus efectos en lactantes y niños pueden diferir a los producidos en adultos, aún cuando ...
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(2009)Olanzapina es un nuevo antipsicótico tienobenzodiazepínico estructuralmente relacionado con clozapina. Esta droga ha demostrado gran eficacia en el tratamiento de pacientes esquizofrénicos, con baja incidencia de efectos ...
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(2012)The aim of this study was to compare the bioavailability of an oral formulation of the coumarin derivative-vitamine K antagonist acenocoumarol (Acebron TM 4 mg, Test) with the reference formulation (Neo-Sintrom TM 4 ...
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(2011-12)Antecedentes: La mayoría de los pacientes que reciben tratamientos con anticoagulantes orales por periodos prolongados presentan variabilidad en la respuesta. El acenocumarol es el anticoagulante oral más prescrito en ...
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(2011)Background: The bioequivalence of different formulations of a same pharmaceutical product must be tested empirically. Aim: To evaluate the relative bioavailability for an oral formulation of mycophenolate mofetil (MMF) ...
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(2011)En el presente trabajo se hace un análisis de los conceptos, normativas y propuestas sobre la equivalencia terapéutica de medicamentos similares con respecto a los innovadores, desde una perspectiva internacional y nacional, ...
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(2008)Pharmacokinetics corresponds to the branch of pharmacology that studies the absorption, distribution, biotransformation and excretion of drugs in the body, in order to proportionate a reference line for interpretation ...
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(2006)Pharmacogenetics is the study of genetically determined variations in the response to drugs and toxic agents, and their implications on disease. Recently, the discipline has acquired great relevancy due to the development ...
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(2009)En los últimos años la ciencia y la tecnología del diagnóstico molecular para probar respuestas individuales o idoneidad para un tratamiento farmacológico ha ido en franco avance, de modo que el laboratorio clínico ha ...
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(2012)Introduction. Levonorgestrel a synthetic progestagen used for endometriosis, dysmenorrhea and emergency contraception, is quickly and completely absorbed in the digestive tract. levonorgestrel is predominantly metabolised ...
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(2006-12)Once drug patents expire, the health authorities can approve the registry of similar products. They must request to the manufacturer the bibliographic background of the original product and the analytical results that ...
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(2006)Once drug patents expire, the health authorities can approve the registry of similar products. They must request to the manufacturer, the bibliographic background of the original product and the analytical results that ...
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(Sociedad de Farmacología de Chile, 2011)Los pacientes psiquiátricos están continuamente sometidos a una amplia gama de medicamentos, entre ellos neurolépticos o antipsicóticos. Enfocándose particularmente en los pacientes que reciben antipsicóticos, es sabido ...
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(2010-05)Polycyclic aromatic hydrocarbons (PAHs) contained in tobacco smoke acquire carcinogenicity following their activation by xenobiotic-metabolizing enzymes to highly reactive metabolites The cytochrome P4501A1 (CYP1A1) enzyme ...
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(Sociedad Médica de Santiago, 2008-10)Cytochrome P450 enzymes are very important to metabolize anti-carcinogenic agents. Therefore, understanding the role of these enzymes and their allele variants in the bioactivation or detoxification of drugs could greatiy ...
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(2010)Changes in bioavailability of anticonvulsant drugs such as topiramate may cause loss of or worsened seizure control. Thus, the purpose of this study was to evaluate, in a double-blind crossover design, the bioavailability ...
