Browsing by Author "82400122-42fa-4077-b23c-a51214dd0baa"
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Benites, Julio; Valderrama, Jaime A.; Ríos, David; Lagos Mónaco, Rosalba; Monasterio Opazo, Octavio; Buc Calderón, Pedro (2016)Dihydroxynaphthyl aryl ketones 1-5 exhibit activity as tubulin polymerization inhibitors by targeting the colchicine binding site of microtubules making them potential anticancer drugs. Therefore, analogues 1-5 have been ...
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Araya Maturana, Ramiro; Cassels Niven, Bruce; Delgado Castro, Tomás; Valderrama, Jaime A.; Weiss López, Boris (Elsevier Ltd, 1999)The Diels-Alder reactions of 8,8-dimethylnaphtalene-1,4,5(8H)-trione with 2,4-hexadien-1-ol and its O-acetyl derivative were investigated in different solvents. The regiochemistry of the cycloaddition of the hexadienol was ...