Browsing by Author "277f6148-043c-4129-b0c7-b39ecee57bc5"

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    • Chronic stress triggers expression of immediate early genes and differentially affects the expression of ... 
      Pacheco Zapata, Aníbal; Aguayo, Felipe I.; Aliaga, Esteban; Muñoz, Mauricio; García Rojo, Gonzalo; Olave, Felipe A.; Parra Fiedler, Nicolás; García Pérez, Alexandra; Tejos Bravo, Macarena; Rojas, Paulina S.; Parra, Claudio S.; Fiedler Temer, Jenny (Frontiers media SA, 2017)
      Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared ...
    • The ROCK inhibitor fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic ... 
      García Rojo, Gonzalo; Fresno, Cristóbal; Vilches Peñaloza, Natalia; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Aguayo Abarca, Felipe; Pacheco Zapata, Aníbal; Parra Fiedler, Nicolás; Parra, Claudio; Rojas Domínguez, Paulina; Tejos Bravo, Macarena; Aliaga, Esteban; Fiedler Temer, Jenny (Oxford University Press, 2017-04-01)
      Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...