Now showing items 1174-1193 of 2543

    • Ibandronate metal complexes: solution behavior and antiparasitic activity 

      Demoro, Bruno; Rostan, Santiago; Moncada, Mauricio; Li, Zhu Hong; Docampo, Roberto; Olea Azar, Claudio; Maya Arango, Juan; Torres, Julia; Gambino, Dinorah; Otero, Lucia (Springer, 2018)
      To face the high costs of developing new drugs, researchers in both industry and academy are looking for ways to repurpose old drugs for new uses. In this sense, bisphosphonates that are clinically used for bone diseases ...
    • Ibuprofen, Carbamazepine and β-Estradiol Determination Using Thin-Film Microextraction and Gas Chromatography-Mass Spectrometry 

      iordano, Ady; Vásquez, José; Retamal, Mauricio; Ascar Estay, María Loreto (Sociedad Brasileira de Quimica, 2016)
      The use of thin-film microextraction for the extraction of selected pharmaceutical compounds followed by gas chromatography-mass spectrometry detection was evaluated. A segment of polysiloxanes polymer sheet was used as ...
    • ICDS 2011 meeting 'Signaling in cell death survival, proliferation and degeneration' 

      Lockshin, R. A.; Smaili, S. S.; Lavandero González, Sergio; Zakeri, Z. (NATURE PUBLISHING GROUP, 2012-01)
      Meeting Report
    • Identificación de barnices en pintura de caballete por cromatografía en placa fina (TLC) y espectroscopía infrarroja (FTIR) 

      Acevedo Ramos, Armando Rodrigo; Eisner Sagüés, Federico; Ossa Izquierdo, Carolina; Zanocco Loyola, Antonio (Dirección de Bibliotecas, Archivos y Museos. Centro Nacional de Conservación y Restauración, 2003)
      Se desarrolló un protocolo de reconocimiento de barnices empleados en pintura de caballetes utilizando Cromatografía en Placa Fina (TLC). La identificación del barníz se realizó comparando el perfil de elusión cromatográfico ...
    • Identification and characterization of GroEL and DnaK homologues in Thiobacillus ferrooxidans 

      Varela, Patricia; Jerez, Carlos A. (1992)
      The major heat shock proteins from Thiobacillus ferrooxidans were identified as DnaK and GroEL equivalents by Western blotting and analysis of the N-terminal amino acid sequence of spots isolated from dried 2-D polyacrylamide ...
    • Identification and subcellular localization of two isoenzymes of apyrase from Solanum tuberosum 

      Kettlun, Ana María; Leyton, Mario; Valenzuela, María Antonieta; Mancilla, Marta; Traverso Cori, A. (1992)
      Two forms of ATP-diphosphohydrolase were identified in Solanum tuberosum tuber var. Ultimus. Their hydrolytic activity ratios (ATPase/ADPase) were over 10 for form A and 1 for form B. In the potato tuber homogenate the ...
    • IDENTIFICATION AND SUBCELLULAR-LOCALIZATION OF 2 ISOENZYMES OF APYRASE FROM SOLANUM-TUBEROSUM 

      Kettlun, Ana María; Leyton, Mario; Valenzuela Pedevila, María Antonieta; Mancilla, Marta; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1992-06)
      Two forms of ATP-diphosphohydrolase were identified in Solanum tuberosum tuber var. Ultimus. Their hydrolytic activity ratios (ATPase/ADPase) were over 10 for form A and 1 for form B. In the potato tuber homogenate the ...
    • Identification of an apyrase activating protein and of calmodulin in Solanum tuberosum 

      Mancilla, Marta; Valenzuela, Marta; Anich, Mario; Kettlun, Ana María; Jara, Otilia; Traverso Cori, A. (1987)
      Three types of effector proteins have been isolated from a partially purified protein preparation of potato tuber. One of the proteins is a typical calmodulin which has no effect on apyrase. The two other proteins modulate ...
    • Identification of lowest excited states in the organometallic iron-nitrile complexes 

      Diaz, Eloisa (1999)
      Electronic absorption spectra for the complexes [CpFe(dppe)NC-R]PF6 R = CH2-C6H4-ON3P3(OC 6H4t-Bu)5 (1), R = CH2-C6H4-OH (2) and R = CH3 (3) in different solvents have been measured. The two absorption bands at the lowest ...
    • Identification of Nosema ceranae in the Valparaíso District, Chile 

      Bravo, J.; Carbonell, V.; Valdebenito, J. T.; Figueroa, C.; Valdovinos, C. E.; Martín-Hernández, R.; Higes, M.; Delporte, C. (Universidad Austral de Chile, 2014)
      This study aimed to demonstrate for the first time the presence of Nosema ceranae in the Valparaiso District. The analised bee samples were obtained in the Valparaiso Region, between 2011 and 2012, from beehives located ...
    • Identification of peptides in flowers of Sambucus nigra with antimicrobial activity against aquaculture pathogens 

      Álvarez, Claudio; Barriga, Andrés; Albericio, Fernando; Romero, María; Guzman, Fanny (MDPI, 2018-05)
      The elder (Sambucus spp.) tree has a number of uses in traditional medicine. Previous studies have demonstrated the antimicrobial properties of elderberry liquid extract against human pathogenic bacteria and also influenza ...
    • Identification of phenolic compounds by HPLC-ESI-MS/MS and antioxidant activity from Chilean propolis 

      Castro, Consuelo; Mura Mardones, Francisco; Valenzuela, Gabriela; Figueroa, Catalina; Salinas, Romina; Zuñiga, M. Carolina; Torres, Josep Lluís; Fuguet, Elisabet; Delporte, Carla (Elsevier Ltd, 2014)
      © 2014.Propolis is a complex hive product produced by honey bees, Apis mellifera. Its composition and biological activities depend on the vegetation where hives are placed. Propolis is often used as a food supplement. The ...
    • Identification of pre-harvest factors that affect fatty acid profiles of avocado fruit (Persea americana Mill) cv. 'Hass' at harvest 

      Ferreyra, R.; Sellés, G. G.; Saavedra, J.; Ortiz, J.; Zúñiga, C.; Troncoso, C.; Rivera, S. A.; González Agüero, M.; Defilippi, B. G (Elsevier, 2016)
      'Hass' avocado is the most important avocado variety cultivated worldwide. In Chile alone, there are nearly 40,000 ha, distributed between the IV and VI regions, with production areas located close to both the coast and ...
    • Identification of the transition state for fast reactions: The trapping of hydroxyl and methyl radicals by DMPO - A DFT approach 

      Aguilera Venegas, Benjamín; Speisky Cosoy, Hernán (Elsevier Inc., 2014)
      Up to date, attempts to locate the transition state (TS) for the trapping reaction between ̇OH and ̇DMPO have been unsuccessful, and the lack of molecular mechanisms by which ̇OH binds to the spin-trap constitutes a question ...
    • IGF-1 modulation of rat cardiac fibroblast behavior and gene expression is age-dependent 

      Díaz Araya, Guillermo; Borg, T. K.; Lavandero González, Sergio; Loftis, M. J.; Carver, W. (TAYLOR & FRANCIS LTD, 2003-05)
      The collagenous extracellular matrix (ECM) forms a stress-tolerant network that is essential for proper function of the vertebrate heart. Profound changes have been detected in the interstitial ECM concurrent with developmental ...
    • IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB 

      Maldonado, Carola; Cea, Paola; Adasme, Tatiana; Collao, Andrés; Díaz Araya, Guillermo; Chiong Lay, Mario; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-11-04)
      Hyperosmotic stress stimulates a rapid and pronounced apoptosis in cardiac myocytes which is attenuated by insulin-like growth factor-1 (IGF-1). Because in these cells IGF-1 induces intracellular Ca2+ increase, we assessed ...
    • IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress 

      Morales, María Paz; Gálvez, Anita; Eltit Ortega, José Miguel; Ocaranza, María Paz; Díaz Araya, Guillermo; Lavandero González, Sergio (ACADEMIC PRESS INC, 2000-04-21)
      Insulin-like growth factor-1 (IGF-1) is a natural protectant of cardiac myocytes that has been shown to improve cardiac function. The role of IGF-1 in attenuating apoptosis induced by osmotic stress (sorbitol, SOR) or by ...
    • IGF-1: Un factor de crecimiento con acciones cardiovasculares pleiotrópicas. 

      Contreras Ferrat, Ariel Eduardo; Aránguiz Urroz, Pablo Daniel; Díaz Elizondo, Jessica; Chiong Lay, Mario; Muñoz, Juan Pablo; Parra Ortíz, María Valentina; Ibarra, Cristián; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo; Eisner, Verónica; Salas, Daniela; Rodríguez Villarroel, Andrea Elizabeth; Carrasco Alarcón, Loreto del Pilar; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      El factor de crecimiento análogo a insulina tipo 1 (IGF-1) es un péptido relacionado estructural y funcionalmente con insulina que posee efectos mitogénicos y citoprotectores. Sus efectos biológicos dependen de la activación ...
    • II-Metossi-diabolina: un nuovo alcaloide terziario da Strychnos Romeu Belenii Krukoff & Barneby 

      Delle Monache, E. M.; Galeffi, Corrado; Erazo, Silvia; Marini-Bettòlo, G. B. (Accademia Nazionale dei Lincei, 1971)
      From the stem bark of Strychnos Romeu Belenii Krukoff & Barneby a Loganiacea of South America, a new indolinic alkaloid has been isolated, to which the structure of II-methoxydiaboline(I) has been assigned on the basis of ...
    • The IKK complex contributes to the induction of autophagy 

      Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Helene; Maiuri, M. C.; Morselli, E.; Vitale, I.; Kepp, O.; Tasdemir, E.; Galluzzi, Lorenzo; Shen, S.; Tailler, M.; Delahaye, N.; Tesniere, A.; De Stefano, D.; Ben Younes, Amena; Harper, F.; Pierron, G.; Lavandero González, Sergio; Zitvogel, L.; Israel, A; Baud, V; Kroemer, Guido (NATURE PUBLISHING GROUP, 2010-02-03)
      In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...