Now showing items 1311-1330 of 2801

    • Maldonado, Carola; Cea, Paola; Adasme, Tatiana; Collao, Andrés; Díaz Araya, Guillermo; Chiong Lay, Mario; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-11-04)
      Hyperosmotic stress stimulates a rapid and pronounced apoptosis in cardiac myocytes which is attenuated by insulin-like growth factor-1 (IGF-1). Because in these cells IGF-1 induces intracellular Ca2+ increase, we assessed ...
    • Morales, María Paz; Gálvez, Anita; Eltit Ortega, José Miguel; Ocaranza, María Paz; Díaz Araya, Guillermo; Lavandero González, Sergio (ACADEMIC PRESS INC, 2000-04-21)
      Insulin-like growth factor-1 (IGF-1) is a natural protectant of cardiac myocytes that has been shown to improve cardiac function. The role of IGF-1 in attenuating apoptosis induced by osmotic stress (sorbitol, SOR) or by ...
    • Contreras Ferrat, Ariel Eduardo; Aránguiz Urroz, Pablo Daniel; Díaz Elizondo, Jessica; Chiong Lay, Mario; Muñoz, Juan Pablo; Parra Ortíz, María Valentina; Ibarra, Cristián; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo; Eisner, Verónica; Salas, Daniela; Rodríguez Villarroel, Andrea Elizabeth; Carrasco Alarcón, Loreto del Pilar; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      El factor de crecimiento análogo a insulina tipo 1 (IGF-1) es un péptido relacionado estructural y funcionalmente con insulina que posee efectos mitogénicos y citoprotectores. Sus efectos biológicos dependen de la activación ...
    • Delle Monache, E. M.; Galeffi, Corrado; Erazo, Silvia; Marini-Bettòlo, G. B. (Accademia Nazionale dei Lincei, 1971)
      From the stem bark of Strychnos Romeu Belenii Krukoff & Barneby a Loganiacea of South America, a new indolinic alkaloid has been isolated, to which the structure of II-methoxydiaboline(I) has been assigned on the basis of ...
    • Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Helene; Maiuri, M. C.; Morselli, E.; Vitale, I.; Kepp, O.; Tasdemir, E.; Galluzzi, Lorenzo; Shen, S.; Tailler, M.; Delahaye, N.; Tesniere, A.; De Stefano, D.; Ben Younes, Amena; Harper, F.; Pierron, G.; Lavandero González, Sergio; Zitvogel, L.; Israel, A; Baud, V; Kroemer, Guido (NATURE PUBLISHING GROUP, 2010-02-03)
      In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...
    • Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Hélène; Maiuri, Maria Chiara; Morselli, Eugenia; Vitale, Ilio; Kepp, Oliver; Tasdemir, Ezgi; Galluzzi, Lorenzo; Shen, Si; Tailler, Maximilien; Delahaye, Nicolas; Tesniere, Antoine; De Stefano, Daniela; Younes, Aména Ben; Harp (Taylor and Francis Inc., 2010)
      Cells respond to stress by activating cytoplasmic mechanisms as well as transcriptional programs that can lead to adaptation or death. Autophagy represents an important cytoprotective response that is regulated by both ...
    • Primo, Emiliano N.; Bollo Dragnic, Soledad; Rubianes, María D.; Rivas, Gustavo A. (Pergamon-Elsevier Science LTD, 2018)
      This work is focused on the critical analysis of the non-covalent modification of a thiolated-gold surface with different grapheneous materials and the covalent attachment of bovine serum albumin (BSA) as a model protein. ...
    • Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • López Ruiz, Beatríz; Sánchez Cabezudo, M.; Richter Duk, Pablo; Mottola, H. A. (AMER CHEMICAL SOC, 1996-05-15)
      The roles of chemical kinetics and mass transfer in two types of bioreactors (packed-column reactors and rotating disk bioreactors), used with continuous-now sample/reagent(s) processing, are discussed in detail. A normalized ...
    • Benavides Farías, Carlos; Gonzales, Luis; Díaz Romero, Manuel; Fuentes, Rodrigo; García, Gonzalo; Palma Behnke, Rodrigo; Ravizza, Catalina (MDPI, 2015)
      This paper aims to analyse the economy-wide implications of a carbon tax applied on the Chilean electricity generation sector. In order to analyse the macroeconomic impacts, both an energy sectorial model and a Dynamic ...
    • Mella Caro, Camila; Quilaqueo, Michelle; Zúñiga, Rommy N.; Troncoso, Elizabeth (MDPI, 2021)
      The aim of this work was to study the impact of the methodology of in vitro gastric digestion (i.e., in terms of motility exerted and presence of gastric emptying) and gel structure on the degree of intestinal proteolysis ...
    • Ureta Zañartú, María Soledad; Méndez Torres, Ana María; Fernández, Francisco; Ilabaca, Jacqueline; Mascayano, Carolina; Gutiérrez, Claudio (Elsevier, 2020)
      In order to determine the possible non-covalent influence of the alkali metal cation on the electrooxidation of 1-heptanol on gold in alkali metal hydroxides, 0.1 M MOH solutions, where M = Li, Na, K, Rb, and Cs, have been ...
    • Sapag Hagar, Mario (Universidad de chile, 1985)
    • Aguilera S., S. María (Sociedad Chilena de la Ciencia del Suelo, 2000)
      Entre los principales intereses mundiales hoy se tiene la gran conciencia del resguardo y recuperación de nuestros principales recursos naturales, entre los cuales es fundamental el sistema edáfico. Los suelos, con fines ...
    • Araya Maturana, Ramiro; Heredia Moya, Jorge; Pessoa Mahana, Hernán; Weiss López, Boris (MARCEL DEKKER INC, 2003)
      Treatment of formylchromones, dissolved in 2-propanol with basic alumina at 75degreesC, selectively reduces the formyl group with good yields without any activation process of the alumina.
    • Atalah Zúñiga, Joaquín Ignacio; Zhou, Yan; Espina, Giannina; Blamey, Jenny M.; Ramasamy, Ramaraja P. (Royal Society of Chemistry, 2018)
      A recombinant laccase from thermophilic bacteria was used to construct an enzyme-multi-walled carbon nanotube composite catalyst, which shows improved stability as a bio-electrocatalyst for the oxygen reduction reaction ...
    • Torrado Salmerón, Carlos; Guarnizo Herrero, Víctor; Gallego Arranz, Teresa; Val-Sabugo, Yvonne del; Torrado, Guillermo; Morales Valenzuela, Javier; Torrado Santiago, Santiago (MDPI, 2020)
      Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the ...
    • Jullian Matthaei, Carolina (2009)
      The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ...
    • Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...